Jeffrey Sivik

TL;DR: Inhibition of a tyrosine kinase, be it c-kit, PDGFRβ or some other undefined target, may improve diabetes mellitus BG control and it deserves further study as a potential novel therapeutic option.

TL;DR: The case of a 49-year-old woman with acute myeloid leukemia who received 4 months of posaconazole as an outpatient for the labeled indication of prophylaxis of Candida and Aspergillus infections, who succumbed to an invasive sinus infection five weeks after presentation is reported.

TL;DR: It is postulated that a finite course of cytotoxic or targeted therapy specific for melanoma given after apparent failure of prior immunotherapy can result in complete and durable remissions that may persist long after the specific cytot toxic or targeted agents have been discontinued suggesting the existence of sequence specific synergism between immunotherapy and these agents.

TL;DR: All patients with IgM MGUS and neuropathy should be screened for anti-MAG antibodies and, if positive, they should be offered treatment with rituximab.

TL;DR: Treatment with thalidomide, lenalidomides, and pomalidomid was associated with various clinical manifestations of central neurotoxicity, including reversible coma, amnesia, expressive aphasia, and dysarthria, which should be recognized as an important side effect of IMiD therapy.