J
Jingguan Lin
Researcher at Central South University
Publications - 19
Citations - 582
Jingguan Lin is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 6, co-authored 6 publications receiving 303 citations.
Papers
More filters
Journal ArticleDOI
Role of the NFκB-signaling pathway in cancer
Longzheng Xia,Shiming Tan,Yujuan Zhou,Jingguan Lin,Heran Wang,Linda Oyang,Yutong Tian,Lu Liu,Min Su,Hui Wang,Deliang Cao,Qianjin Liao +11 more
TL;DR: Current understanding of the NFκB-signaling pathway in cancer is updated and targeted therapies against effectors in oncogenic signaling have improved the outcomes of cancer patients.
Journal ArticleDOI
Cancer stem cells in progression of colorectal cancer.
Yu-juan Zhou,Longzheng Xia,Heran Wang,Linda Oyang,Min Su,Qiang Liu,Jingguan Lin,Shiming Tan,Yutong Tian,Qianjin Liao,Deliang Cao,Deliang Cao +11 more
TL;DR: This review article updates the colorectal CSCs with a focus on their role in tumor initiation, progression, drug resistance and tumor relapse.
Journal ArticleDOI
Exosomes in Nasopharyngeal Carcinoma.
Yujuan Zhou,Longzheng Xia,Jingguan Lin,Heran Wang,Linda Oyang,Shiming Tan,Yutong Tian,Min Su,Hui Wang,Deliang Cao,Deliang Cao,Qianjin Liao +11 more
TL;DR: Clinically, the exosomes may serve as novel biomarkers for diagnosis and targeted therapies of nasopharyngeal carcinoma and may also induce epithelial-mesenchymal transition (EMT), thus promoting tumor metastasis and chemoradioresistance.
Journal ArticleDOI
LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma.
Heran Wang,Yujuan Zhou,Linda Oyang,Yaqian Han,Longzheng Xia,Jingguan Lin,Yanyan Tang,Min Su,Shiming Tan,Yutong Tian,Xiaoyan Chen,Xia Luo,Jiaxin Liang,Shan Rao,Ying Wang,Wei Xiong,Zhaoyang Zeng,Hui Wang,Guiyuan Li,Qianjin Liao +19 more
TL;DR: A novel mechanism underlying the anticancer effect of LPLUNC1 is revealed and it is clarified that PHB1 may represent a novel, promising candidate tumour suppressor gene in NPC, with potential therapeutic target value.
Journal ArticleDOI
Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition
Longzheng Xia,Jingguan Lin,Jian Su,Linda Oyang,Heran Wang,Shiming Tan,Yanyan Tang,Xiaoyan Chen,Wenbin Liu,Xia Luo,Yutong Tian,Jiaxin Liang,Qi Su,Qianjin Liao,Yujuan Zhou +14 more
TL;DR: Rac1 is a potential target molecule for the inhibitory effect of DADS on EMT and invasion and metastasis of colon cancer cells and is associated with aberrant expression of EMT markers and poor prognosis.