J
Joost R. van der Vorst
Researcher at Leiden University Medical Center
Publications - 62
Citations - 4174
Joost R. van der Vorst is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Medicine & Indocyanine green. The author has an hindex of 24, co-authored 41 publications receiving 3529 citations. Previous affiliations of Joost R. van der Vorst include Maastricht University Medical Centre & Leiden University.
Papers
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Journal ArticleDOI
Image-guided cancer surgery using near-infrared fluorescence.
Alexander L. Vahrmeijer,Merlijn Hutteman,Joost R. van der Vorst,Cornelis J. H. Van De Velde,John V. Frangioni +4 more
TL;DR: The concept of NIR fluorescence imaging for cancer surgery is introduced, the clinical trial literature to date is examined, and the key issues pertaining to imaging system and contrast agent optimization are outlined.
Journal ArticleDOI
The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery
Boudewijn E. Schaafsma,J. Sven D. Mieog,Merlijn Hutteman,Joost R. van der Vorst,Peter J. K. Kuppen,Clemens W.G.M. Löwik,John V. Frangioni,Cornelis J.H. van de Velde,Alexander L. Vahrmeijer +8 more
TL;DR: Although non‐targeted and non‐conjugatable, ICG appears to be laying the foundation for more widespread use of NIR fluorescence‐guided surgery, understanding its advantages and limitations is of significant importance.
Journal ArticleDOI
Near-infrared fluorescence-guided resection of colorectal liver metastases.
Joost R. van der Vorst,Boudewijn E. Schaafsma,Merlijn Hutteman,Floris P. R. Verbeek,Gerrit-Jan Liefers,Henk H. Hartgrink,Vincent T.H.B.M. Smit,Clemens W.G.M. Löwik,Cornelis J.H. van de Velde,John V. Frangioni,Alexander L. Vahrmeijer +10 more
TL;DR: If optical imaging, using a contrast agent already approved for other indications, could improve hepatic metastasectomy with curative intent, to optimize dose and timing, and to determine the mechanism of contrast agent accumulation are determined.
Journal ArticleDOI
Optical Image-guided Surgery—Where Do We Stand?
Stijn Keereweer,Stijn Keereweer,Jeroen D. F. Kerrebijn,Pieter B A A van Driel,Bangwen Xie,Eric L. Kaijzel,Thomas J. A. Snoeks,Ivo Que,Merlijn Hutteman,Joost R. van der Vorst,J. Sven D. Mieog,Alexander L. Vahrmeijer,Cornelis J.H. van de Velde,Robert J. Baatenburg de Jong,Clemens W.G.M. Löwik +14 more
TL;DR: In this article, the authors provide an overview of the wide range of molecular contrast agents targeting specific hallmarks of cancer and describe perspectives on its future use in cancer surgery, as well as various techniques, contrast agents, and camera systems that are currently used for image-guided surgery.
Journal ArticleDOI
Toward Optimization of Imaging System and Lymphatic Tracer for Near-Infrared Fluorescent Sentinel Lymph Node Mapping in Breast Cancer
J. Sven D. Mieog,Susan Troyan,Merlijn Hutteman,Merlijn Hutteman,Kevin J. Donohoe,Joost R. van der Vorst,Alan Stockdale,Gerrit-Jan Liefers,Hak Soo Choi,Summer L. Gibbs-Strauss,Hein Putter,Sylvain Gioux,Peter J. K. Kuppen,Yoshitomo Ashitate,Clemens W.G.M. Löwik,Vincent T.H.B.M. Smit,Rafiou Oketokoun,Long Ngo,Cornelis J.H. van de Velde,John V. Frangioni,Alexander L. Vahrmeijer +20 more
TL;DR: The clinical translation of a new NIR fluorescence imaging system and the optimal ICG:HSA dose range for SLN mapping in breast cancer are described and defined.