L
Lifen Ning
Researcher at Wuhan University of Science and Technology
Publications - 5
Citations - 2659
Lifen Ning is an academic researcher from Wuhan University of Science and Technology. The author has contributed to research in topics: Medicine & CD8. The author has an hindex of 2, co-authored 2 publications receiving 1526 citations.
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Journal ArticleDOI
Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19).
Bo Diao,Chenhui Wang,Yingjun Tan,Xiewan Chen,Ying Liu,Lifen Ning,Li Chen,Min Li,Yueping Liu,Gang Wang,Zilin Yuan,Zeqing Feng,Yi Zhang,Yuzhang Wu,Yongwen Chen +14 more
TL;DR: T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted, and non-ICU patients with total T cells counts lower than 800/μL may still require urgent intervention, even in the immediate absence of more severe symptoms.
Posted ContentDOI
Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)
Bo Diao,Chenhui Wang,Yingjun Tan,Xiewan Chen,Ying Liu,Lifen Ning,Li Chen,Min Li,Yueping Liu,Gang Wang,Zilin Yuan,Zeqing Feng,Yuzhang Wu,Yongwen Chen +13 more
TL;DR: T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted, with patients in decline period showing reduced IL-6, IL-10 and TNF-α concentrations and restored T cell counts.
Journal ArticleDOI
Antifungal susceptibility profiles and drug resistance mechanisms of clinical Candida duobushaemulonii isolates from China
Xin-Fei Chen,Han Zhang,Xin-miao Jia,Jin Cao,Lin Li,Xin-Lan Hu,Ning Li,Yu Xiao,Fei Xia,Li Ye,Qingna Hu,Xiao-Li Wu,Lifen Ning,Po-Ren Hsueh,Xin Fan,Shu-Ying Yu,Jing-Jing Huang,Xiu-Li Xie,Wen-Hang Yang,Ying-xing Li,Ge Zhang,Jingjing Zhang,Simeng Duan,Wei Kang,Tong Wang,Jin Li,Meng Xiao,Xin Hou,Ying-Chun Xu +28 more
TL;DR: Wang et al. as discussed by the authors collected 11 strains of C. duobushaemulonii from China Hospital Invasive Fungal Surveillance Net (CHIF-NET) and identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF), VITEK 2 Yeast Identification Card (YST), and internal transcribed spacer (ITS) sequencing.
Journal ArticleDOI
First two fungemia cases caused by Candida haemulonii var. vulnera in China with emerged antifungal resistance
Xin-Fei Chen,Xin Hou,Han Zhang,Xin-miao Jia,Lifen Ning,Weisheng Cao,Xin Fan,Jing-Jing Huang,Wen-Hang Yang,Ge Zhang,Jingjia Zhang,Wei Kang,Meng Xiao,Ying-Chun Xu +13 more
TL;DR: In this article , two strains of C. haemulonii var. vulnera were collected from the China Hospital Invasive Fungal Surveillance Net (CHIF-NET), and the identification capacity of three matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and VITEK 2 YST ID biochemical methods were evaluated against ITS sequencing.
Journal ArticleDOI
A comparative study of gastric adenocarcinoma HER2 IHC phenotype and mass spectrometry-based quantification
Bin Xu,Hui Chen,Jingjing Zhang,Yang Cong,Lifen Ning,Limin Chen,Yushi Zhang,Yong Zhang,Zhan-Chun Song,Yuan Meng,Lian-zhi He,Wei Liao,Ying Lu,Fengyi Zhao +13 more
TL;DR: Wang et al. as discussed by the authors presented a new HER2 protein detection method based on mass spectrometry selected reaction monitoring (MS-SRM) and validated the method using large-scale clinical validation.