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Yingjun Tan
Researcher at Third Military Medical University
Publications - 10
Citations - 3734
Yingjun Tan is an academic researcher from Third Military Medical University. The author has contributed to research in topics: CD8 & T cell. The author has an hindex of 7, co-authored 9 publications receiving 2286 citations.
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Journal ArticleDOI
Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19).
Bo Diao,Chenhui Wang,Yingjun Tan,Xiewan Chen,Ying Liu,Lifen Ning,Li Chen,Min Li,Yueping Liu,Gang Wang,Zilin Yuan,Zeqing Feng,Yi Zhang,Yuzhang Wu,Yongwen Chen +14 more
TL;DR: T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted, and non-ICU patients with total T cells counts lower than 800/μL may still require urgent intervention, even in the immediate absence of more severe symptoms.
Posted ContentDOI
Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)
Bo Diao,Chenhui Wang,Yingjun Tan,Xiewan Chen,Ying Liu,Lifen Ning,Li Chen,Min Li,Yueping Liu,Gang Wang,Zilin Yuan,Zeqing Feng,Yuzhang Wu,Yongwen Chen +13 more
TL;DR: T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted, with patients in decline period showing reduced IL-6, IL-10 and TNF-α concentrations and restored T cell counts.
Posted ContentDOI
Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
Bo Diao,Changzheng Wang,Rongshuai Wang,Zeqing Feng,Yingjun Tan,Hang Wang,Lei Liu,Yueping Liu,Gang Wang,Zilin Yuan,Li Ren,Yuzhang Wu,Chen Y +12 more
TL;DR: A retrospective analysis of estimated glomerular filtration rate (eGFR) along with other clinical parameters from 85 patients with laboratory-confirmed COVID-19 admitted to a hospital in Wuhan from January 17, 2020 to March 3, 2020 found that SARS-CoV-2 induces ARF in CO VID-19 patients.
Posted ContentDOI
The Novel Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2) Directly Decimates Human Spleens and Lymph Nodes
Yongwen Chen,Zeqing Feng,Bo Diao,Rongshuai Wang,Gang Wang,Chenhui Wang,Yingjun Tan,Liang Liu,Changsong Wang,Ying Liu,Yueping Liu,Zilin Yuan,Liang Ren,Yuzhang Wu +13 more
TL;DR: It is demonstrated that SARS-CoV-2 directly neutralizes human spleens and LNs through infecting tissue- resident CD169+ macrophage, and triggers macrophages to produce IL-6, a proinflammatory cytokine that directly promotes lymphocyte necrosis.
Journal ArticleDOI
Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection.
Bo Diao,Chenhui Wang,Rongshuai Wang,Zeqing Feng,Ji Zhang,Han Yang,Yingjun Tan,Huiming Wang,Changsong Wang,Liang Liu,Ying Liu,Yueping Liu,Gang Wang,Zilin Yuan,Xiaotao Hou,Liang Ren,Yuzhang Wu,Yongwen Chen +17 more
TL;DR: Wang et al. as mentioned in this paper performed a retrospective analysis of clinical parameters from 85 patients with laboratory-confirmed coronavirus disease 2019 (COVID-19); moreover, kidney histopathology from six additional COVID-2019 patients with post-mortem examinations was performed.