Y
Yi Zhang
Researcher at Third Military Medical University
Publications - 78
Citations - 2539
Yi Zhang is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 15, co-authored 50 publications receiving 1635 citations.
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Journal ArticleDOI
Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19).
Bo Diao,Chenhui Wang,Yingjun Tan,Xiewan Chen,Ying Liu,Lifen Ning,Li Chen,Min Li,Yueping Liu,Gang Wang,Zilin Yuan,Zeqing Feng,Yi Zhang,Yuzhang Wu,Yongwen Chen +14 more
TL;DR: T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted, and non-ICU patients with total T cells counts lower than 800/μL may still require urgent intervention, even in the immediate absence of more severe symptoms.
Journal Article
Mechanism, safety and efficacy of three tyrosine kinase inhibitors lapatinib, neratinib and pyrotinib in HER2-positive breast cancer.
TL;DR: This paper focuses on three officially approved TKIs for HER2 breast cancer, namely, lapatinib, neratinib and pyrotinib, and systematically reviews the mechanism, safety, efficacy and resistance of these TK is.
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SARS-CoV-2 Induces Lymphocytopenia by Promoting Inflammation and Decimates Secondary Lymphoid Organs.
Qun Xiang,Zeqing Feng,Bo Diao,Chao Tu,Qinghua Qiao,Han Yang,Yi Zhang,Gang Wang,Huiming Wang,Chenhui Wang,Liang Liu,Changsong Wang,Longding Liu,Rong Chen,Yuzhang Wu,Yongwen Chen +15 more
TL;DR: Wang et al. as mentioned in this paper retrospectively reviewed the clinical and immunological data from 18 fatal coronavirus disease 2019 (COVID-19) cases, results showed that these patients had severe lymphocytopenia, together with high serum levels of inflammatory cytokines (IL-6, IL-8 and IL-10), and elevation of many other mediators in routine laboratory tests, including C-reactive protein, lactate dehydrogenase, α-hydroxybutyrate dehydrogenase and natriuretic peptide type B.
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Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls.
TL;DR: It can be concluded that potentially functional MTHFR C677T polymorphism may play a low penetrance role in the development of breast cancer.
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Plasma prolactin and breast cancer risk: a meta- analysis
TL;DR: Evidence is provided supporting a significantly positive association between plasma prolactin levels and the risk of breast cancer among the patients who were postmenopausal, ER+/PR+ or in situ and invasive carcinoma.