M
Maaz S. Ahmed
Researcher at Harvard University
Publications - 13
Citations - 887
Maaz S. Ahmed is an academic researcher from Harvard University. The author has contributed to research in topics: Catalysis & Carboxylic acid. The author has an hindex of 8, co-authored 12 publications receiving 548 citations. Previous affiliations of Maaz S. Ahmed include University of Wisconsin-Madison & Wisconsin Alumni Research Foundation.
Papers
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Journal ArticleDOI
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.
Christopher B. Rodell,Sean P. Arlauckas,Michael F. Cuccarese,Christopher Garris,Ran Li,Maaz S. Ahmed,Rainer H. Kohler,Mikael J. Pittet,Ralph Weissleder +8 more
TL;DR: The ability of rationally engineered drug–nanoparticle combinations to efficiently modulate tumour-associated macrophages for cancer immunotherapy is demonstrated and R848, an agonist of the toll-like receptors TLR7 and TLR8 identified in a morphometric-based screen, is a potent driver of the M1 phenotype in vitro.
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Discovery of Multicomponent Heterogeneous Catalysts via Admixture Screening: PdBiTe Catalysts for Aerobic Oxidative Esterification of Primary Alcohols
TL;DR: The utility of "admixture screening" for the discovery of new multicomponent heterogeneous Pd catalyst compositions that are highly effective for aerobic oxidative methyl esterification of primary alcohols is demonstrated.
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Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy.
TL;DR: The findings demonstrate the ability of strong nanoparticle-drug interactions to limit systemic toxicity of TLR agonists while simultaneously maintaining therapeutic efficacy.
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Aerobic Oxidation of Diverse Primary Alcohols to Carboxylic Acids with a Heterogeneous Pd–Bi–Te/C (PBT/C) Catalyst
TL;DR: In this article, a heterogeneous catalyst composed of Pd, Bi, and Te supported on activated carbon is proposed for the oxidation of diverse benzylic and aliphatic primary alcohols, including 5-(hydroxymethyl)furfural (HMF) and substrates bearing heterocycles and other important functional groups.
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Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging.
TL;DR: An ultra-fast, highly efficient cycling method based on unique linkers for tetrazine / trans- cyclooctene mediated quenching that allowed multi-cycle staining and immune cell profiling within an hour, leveraging the accelerated kinetics to open new diagnostic possibilities for rapid cellular analyses.