M
Marvin Lim
Researcher at Trinity College, Dublin
Publications - 7
Citations - 605
Marvin Lim is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Prostate cancer & RNA. The author has an hindex of 5, co-authored 7 publications receiving 423 citations. Previous affiliations of Marvin Lim include Tallaght Hospital.
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Journal ArticleDOI
Circular RNAs: Biogenesis, Function and Role in Human Diseases.
John Greene,John Greene,Anne-Marie Baird,Lauren Brady,Marvin Lim,Steven G. Gray,Raymond S. McDermott,Stephen P. Finn +7 more
TL;DR: It has been proposed that circRNA regulate gene expression at the transcriptional or post-transcriptional level by interacting with miRNAs and that circRNAs may have a role in regulating miRNA function in cancer initiation and progression.
Journal ArticleDOI
Impact of body composition parameters on clinical outcomes in patients with metastatic castrate-resistant prostate cancer treated with docetaxel.
S. Cushen,Derek G. Power,Kevin P. Murphy,Ray McDermott,Brendan T. Griffin,Marvin Lim,Louise E. Daly,Peter MacEneaney,Kathleen O' Sullivan,Carla M. Prado,Aoife M. Ryan +10 more
TL;DR: Sarcopenia and low MA are associated with neutropenia (grade I-II) and presence of anaemia, high volume of visceral fat and BMI <25 kg/m2 areassociated with reduced survival in patients with castrate resistant prostate cancer being treated with docetaxel chemotherapy.
Journal ArticleDOI
Circular RNAs are differentially expressed in prostate cancer and are potentially associated with resistance to enzalutamide.
John Greene,Anne-Marie Baird,Orla Casey,Lauren Brady,Gordon Blackshields,Marvin Lim,Marvin Lim,Odharnaith O'Brien,Steven G. Gray,Raymond S. McDermott,Raymond S. McDermott,Stephen P. Finn +11 more
TL;DR: This is one of the first studies to profile and demonstrate discrete circRNAs expression patterns in an enzalutamide resistant cell line model of prostate cancer, and suggests that hsa_circ_0004870, through RBM39, may play a critical role in the development of enzyme resistance in CRPC.
Journal ArticleDOI
Carcinogenesis in prostate cancer: The role of long non-coding RNAs
John Aird,Anne-Marie Baird,Marvin Lim,Marvin Lim,Ray McDermott,Stephen P. Finn,Steven G. Gray +6 more
TL;DR: The role of 34 lncRNAs in prostate cancer is summarized with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.
Journal ArticleDOI
RNAs as Candidate Diagnostic and Prognostic Markers of Prostate Cancer—From Cell Line Models to Liquid Biopsies
Marvin Lim,Anne-Marie Baird,Anne-Marie Baird,John Aird,John Greene,Dhruv Kapoor,Steven G. Gray,Steven G. Gray,Ray McDermott,Stephen P. Finn +9 more
TL;DR: This review focuses on the evidence for the role of RNAs in prostate cancer, and their use as diagnostic and prognostic markers, and targets for treatment in this disease.