M
Maryam Rakhshandehroo
Researcher at Wageningen University and Research Centre
Publications - 18
Citations - 1851
Maryam Rakhshandehroo is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Adipogenesis & Adipose tissue. The author has an hindex of 8, co-authored 17 publications receiving 1705 citations. Previous affiliations of Maryam Rakhshandehroo include University Medical Center Utrecht.
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Journal ArticleDOI
Peroxisome Proliferator-Activated Receptor Alpha Target Genes
TL;DR: An overview of the involvement of PPARα in lipid metabolism and other pathways through a detailed analysis of the different known or putative PPAR α target genes is presented.
Journal ArticleDOI
Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human
TL;DR: The results suggest that PPARα activation has a major impact on gene regulation in human hepatocytes, and the role of PPAR α as master regulator of hepatic lipid metabolism is generally well-conserved between mouse and human.
Journal ArticleDOI
Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling.
Maryam Rakhshandehroo,Linda M. Sanderson,Merja Matilainen,Rinke Stienstra,Carsten Carlberg,Philip J. de Groot,Michael Müller,Sander Kersten +7 more
TL;DR: In this paper, the power of transcriptional profiling to uncover novel PPARα-regulated genes and pathways in liver was illustrated, using an in silico screening approach, one or more PPAR response elements were identified in each of these genes.
Journal ArticleDOI
Natural killer T cells in adipose tissue prevent insulin resistance
Henk S. Schipper,Maryam Rakhshandehroo,Stan F.J. van de Graaf,Koen Venken,Arjen Koppen,Rinke Stienstra,Serge Prop,Jenny Meerding,Nicole Hamers,Gurdyal S. Besra,Louis Boon,Edward E. S. Nieuwenhuis,Dirk Elewaut,Berent J. Prakken,Sander Kersten,Marianne Boes,Eric Kalkhoven +16 more
TL;DR: It is proposed that, especially under low-fat diet conditions, adipose tissue-resident iNKT cells maintain healthy adipose tissues through direct interplay with adipocytes and prevent insulin resistance.
Journal ArticleDOI
Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.
Yuan Gao,Arjen Koppen,Maryam Rakhshandehroo,Ismayil Tasdelen,Stan F.J. van de Graaf,Jorg van Loosdregt,Olivier van Beekum,Nicole Hamers,Dik van Leenen,Celia R. Berkers,Ruud Berger,Frank C. P. Holstege,Paul J. Coffer,Paul J. Coffer,Arjan B. Brenkman,Huib Ovaa,Eric Kalkhoven,Eric Kalkhoven +17 more
TL;DR: It is shown that the expression of the Tip60 protein, which is essential for adipocyte differentiation, is regulated through polyubiquitination on multiple residues, a key mechanism in the regulation of early adipogenesis.