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Rinke Stienstra

Researcher at Wageningen University and Research Centre

Publications -  107
Citations -  5849

Rinke Stienstra is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Adipose tissue & Inflammation. The author has an hindex of 37, co-authored 91 publications receiving 4707 citations. Previous affiliations of Rinke Stienstra include Radboud University Nijmegen Medical Centre & Radboud University Nijmegen.

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Kupffer cells promote hepatic steatosis via interleukin-1β–dependent suppression of peroxisome proliferator-activated receptor α activity

Rinke Stienstra, +8 more
- 01 Feb 2010 - 
TL;DR: In this article, the effect of Kupffer cells on hepatic triglyceride storage was investigated in mice rendered obese and steatotic by chronic high-fat feeding were treated for 1 week with clodronate liposomes.
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Adipose tissue macrophages: going off track during obesity

Lily Boutens, +1 more
- 03 Mar 2016 - 
TL;DR: This review is specifically focused on the contribution of macrophages that reside in adipose tissue in lean and obese conditions and how these changes affect adipOSE tissue inflammation and may be targeted for therapeutic interventions to improve insulin sensitivity in obese individuals.
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PPARs, Obesity, and Inflammation.

Rinke Stienstra, +3 more
- 01 Jan 2007 - 
TL;DR: The role of PPARs in obesity-induced inflammation specifically in adipose tissue, liver, and the vascular wall is addressed, with a growing recognition that obesity represents a state of chronic low-level inflammation.
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The role and regulation of the peroxisome proliferator activated receptor alpha in human liver.

Sander Kersten, +1 more
- 01 May 2017 - 
TL;DR: In addition to helping to correct dyslipidemia, PPARα agonists may hold promise as a therapy for patients with cholestatic liver diseases, non-alcoholic fatty liver disease, and/or type 2 diabetes.
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Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes

Ekta Lachmandas, +14 more
- 01 Mar 2017 - 
TL;DR: Unlike LPS, complex microbial stimuli and the TLR2 ligand P3C induce a specific pattern of metabolic rewiring that involves upregulation of both glycolysis and OXPHOS, which enables activation of host defence mechanisms such as cytokine production and phagocytosis.