Simone A. Joosten

TL;DR: Efforts are needed to reduce the gap between the exploratory up-stream identification of candidate biomarkers, and the validation of biomarkers against clear clinical endpoints in different populations, which will need a major commitment from both scientists and funding bodies.

TL;DR: Presensitization and late acute rejection episodes were the risk factors identified and glomerular C4d deposits suggest that chronic transplant glomerulopathy emerges from in situ humoral rejection.

TL;DR: A review of the altered clinical presentation of TB in the context of T2DM comorbidity, changes in innate and adaptive immune responses, including lymphocyte subsets and T‐cell phenotypes, the effect of treatment of the differentComorbidities,Changes in biomarker expression and genetic predisposition to the respective morbidities, and other factors affecting the comorbbidity are discussed.

TL;DR: The role of direct and indirect antigen presentation is discussed, and the production of antibodies directed against HLA and non-HLA antigens on the graft and their influence on CR are focused on.

TL;DR: Targeted tandem liquid chromatography–mass spectrometry was used to compare amine and acylcarnitine levels in plasma samples of patients with TB or TB-DM from Indonesia at time of diagnosis and during antibiotic treatment, and significantly enhance the understanding of metabolic changes in human TB andTB-DM.