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Elisa Petruccioli
Researcher at Istituto Superiore di Sanità
Publications - 50
Citations - 1880
Elisa Petruccioli is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Tuberculosis & Latent tuberculosis. The author has an hindex of 20, co-authored 45 publications receiving 1395 citations. Previous affiliations of Elisa Petruccioli include University of Rome Tor Vergata.
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Journal ArticleDOI
Mycobacterium Tuberculosis-Specific CD8+ T Cells Are Functionally and Phenotypically Different Between Latent Infection and Active Disease
Virginie Rozot,Selena Vigano,Jesica Mazza-Stalder,Elita Idrizi,Cheryl L. Day,Matthieu Perreau,Catherine Lazor-Blanchet,Elisa Petruccioli,Willem A. Hanekom,Delia Goletti,Pierre-Alexandre Bart,Laurent P. Nicod,Giuseppe Pantaleo,Alexandre Harari +13 more
TL;DR: The activity of Mt b infection and clinical presentation are associated with distinct profiles of Mtb‐specific CD8+ T‐cell responses, and these results provide new insights in the interaction between Mtb and the host immune response.
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Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis.
Elisa Petruccioli,Thomas J. Scriba,Linda Petrone,Mark Hatherill,Mark Hatherill,Daniela Maria Cirillo,Simone A. Joosten,Tom H. M. Ottenhoff,Claudia M. Denkinger,Delia Goletti +9 more
TL;DR: Future studies are needed to determine whether correlates of risk can be used to prevent active TB through targeted prophylactic treatment, or to allow targeted enrolment into efficacy trials of new TB vaccines and therapeutic drugs.
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Tuberculosis Biomarkers: From Diagnosis to Protection
TL;DR: Efforts are needed to reduce the gap between the exploratory up-stream identification of candidate biomarkers, and the validation of biomarkers against clear clinical endpoints in different populations, which will need a major commitment from both scientists and funding bodies.
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IFNγ/TNFα specific-cells and effector memory phenotype associate with active tuberculosis
Elisa Petruccioli,Linda Petrone,Valentina Vanini,Alessandro Sampaolesi,Gina Gualano,Enrico Girardi,Fabrizio Palmieri,Delia Goletti +7 more
TL;DR: Qualitative associations between Mtb-specific T-cell and TB status in terms of functional capacity and memory status are identified and may be helpful to trace natural history of TB.
Journal ArticleDOI
A whole blood test to measure SARS-CoV-2-specific response in COVID-19 patients.
Linda Petrone,Elisa Petruccioli,Valentina Vanini,Gilda Cuzzi,Saeid Najafi Fard,Tonino Alonzi,Concetta Castilletti,Fabrizio Palmieri,Gina Gualano,Pietro Vittozzi,Emanuele Nicastri,Luciana Lepore,Andrea Antinori,Alessandra Vergori,Nadia Caccamo,Fabrizio Cantini,Enrico Girardi,Giuseppe Ippolito,Alba Grifoni,Delia Goletti +19 more
TL;DR: Immune response to SARS-CoV-2 peptides in a whole-blood assay is associated to COVID-19 and it is characterized by both Th1 and Th2 profile, which may be useful for developing new T-cell based diagnostic tests for disease and vaccine settings.