T
Tolison Fowler
Researcher at Washington University in St. Louis
Publications - 1
Citations - 227
Tolison Fowler is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Cancer epigenetics & Epigenomics. The author has an hindex of 1, co-authored 1 publications receiving 188 citations.
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Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation
James I. McDonald,Hamza Celik,Lisa E. Rois,Gregory Fishberger,Tolison Fowler,Ryan Rees,Ashley C. Kramer,Andrew Martens,John R. Edwards,Grant A. Challen +9 more
TL;DR: A CRISPR/dCas9-DNMT3A fusion protein to repress the expression of endogenous genes in combination with multiple guide RNAs can help to elucidate the role of DNA methylation in normal development and disease.