Journal•ISSN: 1471-4906
Trends in Immunology
Elsevier BV
About: Trends in Immunology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Immune system & T cell. It has an ISSN identifier of 1471-4906. Over the lifetime, 2421 publications have been published receiving 254882 citations.
Papers published on a yearly basis
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TL;DR: Recent evidence suggests that differential modulation of the chemokine system integrates polarized macrophages in pathways of resistance to, or promotion of, microbial pathogens and tumors, or immunoregulation, tissue repair and remodeling.
5,568 citations
TL;DR: These functionally polarized cells, and similarly oriented or immature dendritic cells present in tumors, have a key role in subversion of adaptive immunity and in inflammatory circuits that promote tumor growth and progression.
4,728 citations
TL;DR: Human natural killer cells comprise approximately 15% of all circulating lymphocytes and have the capacity to produce abundant cytokines following activation of monocytes, but has low natural cytotoxicity and is CD16(dim) or CD16(-).
2,693 citations
TL;DR: These findings suggest that targeting proinflammatory cytokines and their signaling pathways might represent a novel strategy to treat depression.
2,608 citations
TL;DR: Results strongly suggest that the classical and alternative pathways to NF-κB activation have distinct regulatory functions, one that is mostly involved in innate immunity and the other in adaptive immunity.
2,393 citations