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Open AccessJournal ArticleDOI

A Systematic Review on the Efficacy and Safety of Chloroquine for the Treatment of COVID-19

Andrea Cortegiani, +4 more
- 10 Mar 2020 - 
- Vol. 57, pp 279-283
TLDR
There is rationale, pre-clinical evidence of effectiveness and evidence of safety from long-time clinical use for other indications to justify clinical research on chloroquine in patients with COVID-19.
About: 
This article is published in Journal of Critical Care.The article was published on 2020-03-10 and is currently open access. It has received 870 citations till now. The article focuses on the topics: Clinical trial & Clinical research.

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Citations
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Identifying social perceptions of people ignoring COVID-19 warnings: a qualitative study in Iran.

Zohreh Halvaiepour, +1 more
- 27 Sep 2021 - 
TL;DR: In this paper, a qualitative study was carried out from May to July 2020 to identify the sociological perceptions of people who ignore the COVID-19 warning, and the saturation point was reached in 20 semi-structured interviews.
Journal ArticleDOI

Association Rules Extraction From the Coronavirus Disease 2019: Attributes on Morbidity and Mortality

Donald Douglas Atsa'am, +1 more
- 01 Jan 2022 - 
TL;DR:
Journal ArticleDOI

QT interval and repolarization dispersion changes during the administration of hydroxychloroquine/chloroquine with/without azithromycin in early COVID 19 pandemic: A prospective observational study from two academic hospitals in Indonesia.

Rizki Amalia Gumilang, +5 more
- 28 Aug 2021 - 
TL;DR: In this paper, a prospective observational study was performed in two academic hospitals in Indonesia to investigate QTc interval and ventricular repolarization dispersion changes, as markers of arrhythmia risks, after HCQ/CQ administration with/without azithromycin (AZT) during COVID-19 pandemic.
Journal ArticleDOI

Antimalarial chloroquine indicated for viral infections: myth ou hope?

Guilherme Marinho Sampaio, +15 more
- 16 Aug 2021 - 
TL;DR: Chloroquine seems to have potential antivirotic properties that may be useful in the treatment of the grave acute forms of COVID-19 associated with Azithromycin, but its indication must include ECG monitoring due to the risk of cardiac QT prolongation able to cause sudden deaths.
DOI

Chloroquine and hydroxychloroquine in Brazil: a case of inefficacy in public health management/ Cloroquina e hidroxicloroquina no Brasil: um caso de ineficácia na gestão da saúde pública/ La cloroquina y la hidroxicloroquina en el Brasil: un caso de ineficacia en la salud

Diego de Oliveira Souza
TL;DR: A revisao de literatura as discussed by the authors revealed that ainda nao ha eficacia clinica comprovada no uso da cloroquina and da hidroxicloroquina contra a Covid-19.
References
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Journal ArticleDOI

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang, +28 more
- 24 Jan 2020 - 
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
Journal ArticleDOI

Clinical Characteristics of Coronavirus Disease 2019 in China.

Wei-jie Guan, +36 more
- 28 Feb 2020 - 
TL;DR: During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness, and patients often presented without fever, and many did not have abnormal radiologic findings.
Journal ArticleDOI

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

Dawei Wang, +13 more
- 17 Mar 2020 - 
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

Zunyou Wu, +1 more
- 07 Apr 2020 - 
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.

Xiaobo Yang, +17 more
- 01 May 2020 - 
TL;DR: The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.
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