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Open AccessJournal ArticleDOI

A Systematic Review on the Efficacy and Safety of Chloroquine for the Treatment of COVID-19

TLDR
There is rationale, pre-clinical evidence of effectiveness and evidence of safety from long-time clinical use for other indications to justify clinical research on chloroquine in patients with COVID-19.
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This article is published in Journal of Critical Care.The article was published on 2020-03-10 and is currently open access. It has received 870 citations till now. The article focuses on the topics: Clinical trial & Clinical research.

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Uso de aminoquinolinas (Cloroquina e Hidroxicloroquina) no tratamento da COVID-19: uma revisão sistemática

TL;DR: O presente estudo possui o objetivo of avaliar a eficácia da HCQ e CQ no tratamento de pacientes com COVID-19, por meio da realização of uma revisão sistemática dos principais artigos envolvendo pacients com CO VID-19 e o uso of HCQ and CQ.
Journal ArticleDOI

A new challenge for ‘Dental Professionals’ during this pandemic situation of COVID-19

TL;DR: A protocol of management from available literatures is presented which help to formulate a possible plan for evaluation and prevention of COVID 19 from patients to dental practitioner or vice versa.
Journal ArticleDOI

Clinical Characteristics and Mathematical Analysis of Curative Effect of Hemodialysis in Curing Poisoning Caused by Snakebite

TL;DR: It is proved that continuous hemodiafiltration combined with plasma exchange treatment can effectively improve the blood coagulation index and myocardial index of severe snakebite poisoning patients.
Journal ArticleDOI

Potential antiviral effect of chloroquine therapy against sars-cov-2 infection

TL;DR: Chloroquine has promising antiviral effects on SARS-CoV-2 at different levels, and may be a potential choice in the absence of an effective vaccine and medication.
Posted ContentDOI

Immunobiochemical Aspects in the Pathogenesis, Diagnosis, and Management of Novel Coronavirus (SARS-Cov-2) Infection

TL;DR: An increased understanding of the immunobiochemical aspects of the disease may contribute to better management of SARS-CoV-2-infected persons, as evidenced from the available literature.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
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