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Open AccessJournal ArticleDOI

A Systematic Review on the Efficacy and Safety of Chloroquine for the Treatment of COVID-19

Andrea Cortegiani, +4 more
- 10 Mar 2020 - 
- Vol. 57, pp 279-283
TLDR
There is rationale, pre-clinical evidence of effectiveness and evidence of safety from long-time clinical use for other indications to justify clinical research on chloroquine in patients with COVID-19.
About: 
This article is published in Journal of Critical Care.The article was published on 2020-03-10 and is currently open access. It has received 870 citations till now. The article focuses on the topics: Clinical trial & Clinical research.

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COVID-19 and Fake News in the Dominican Republic.

Leandro Tapia
- 29 Apr 2020 - 
TL;DR: Within 45 days of the first reported case, the political crisis and turmoil caused by “fake news” are limiting the capacity and success of the MoH response to the pandemic.
Journal ArticleDOI

Real-World Issues and Potential Solutions in Hematopoietic Cell Transplantation during the COVID-19 Pandemic: Perspectives from the Worldwide Network for Blood and Marrow Transplantation and Center for International Blood and Marrow Transplant Research Health Services and International Studies Committee.

Ghada Algwaiz, +39 more
- 01 Dec 2020 - 
TL;DR: An expert opinion statement is produced as a general guide to deal with certain aspects of HCT, including diagnostics for SARS-CoV-2 in HCT recipient, pre- and post-HCT management, donor issues, medical tourism, and facilities management.
Journal ArticleDOI

Targeting Neprilysin (NEP) pathways: A potential new hope to defeat COVID-19 ghost.

Manar Mohammed El Tabaa, +1 more
- 27 May 2020 - 
TL;DR: The review aimed to shed light on the potential beneficial effects of NEP pathways as a novel target for COVID-19 therapy by summarizing its possible molecular mechanisms.
Journal ArticleDOI

Chloroquine as a prophylactic agent against COVID-19?

Mathieu Gendrot, +4 more
- 12 Apr 2020 - 
TL;DR: Prophylactic use of chloroquine or hydroxychloroquine in COVID-19 is considered and effectiveness of these drugs in treatment is discussed.
Journal ArticleDOI

Understanding COVID-19 Pandemic: Molecular Mechanisms and Potential Therapeutic Strategies. An Evidence-Based Review

Reem Hanna, +5 more
- 01 Jan 2021 - 
TL;DR: In this article, the authors conducted a critical review of the literature, focusing on the current molecular structure of SARS-CoV-2 and prospective treatment modalities of COVID-19.
References
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Journal ArticleDOI

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang, +28 more
- 24 Jan 2020 - 
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
Journal ArticleDOI

Clinical Characteristics of Coronavirus Disease 2019 in China.

Wei-jie Guan, +36 more
- 28 Feb 2020 - 
TL;DR: During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness, and patients often presented without fever, and many did not have abnormal radiologic findings.
Journal ArticleDOI

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

Dawei Wang, +13 more
- 17 Mar 2020 - 
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

Zunyou Wu, +1 more
- 07 Apr 2020 - 
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.

Xiaobo Yang, +17 more
- 01 May 2020 - 
TL;DR: The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang, +28 more
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

Nanshan Chen, +13 more
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

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Clinical Characteristics of Coronavirus Disease 2019 in China.

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