Journal ArticleDOI
Evolving concepts in biofilm infections
TLDR
Several pathogens associated with chronic infections, including Pseudomonas aeruginosa in cystic fibrosis pneumonia, Haemophilus influenzae and Streptococcus pneumoniae in chronic otitis media, and enteropathogenic Escherichia coli in recurrent urinary tract infections, are linked to biofilm formation.Abstract:
Several pathogens associated with chronic infections, including Pseudomonas aeruginosa in cystic fibrosis pneumonia, Haemophilus influenzae and Streptococcus pneumoniae in chronic otitis media, Staphylococcus aureus in chronic rhinosinusitis and enteropathogenic Escherichia coli in recurrent urinary tract infections, are linked to biofilm formation. Biofilms are usually defined as surface-associated microbial communities, surrounded by an extracellular polymeric substance (EPS) matrix. Biofilm formation has been demonstrated for numerous pathogens and is clearly an important microbial survival strategy. However, outside of dental plaques, fewer reports have investigated biofilm development in clinical samples. Typically biofilms are found in chronic diseases that resist host immune responses and antibiotic treatment and these characteristics are often cited for the ability of bacteria to persist in vivo. This review examines some recent attempts to examine the biofilm phenotype in vivo and discusses the challenges and implications for defining a biofilm phenotyperead more
Citations
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Journal ArticleDOI
Study of the Adhesion of Clinical Strains of Staphylococcus Aureus on an Abiotic Surface Using the Biofilm Ring Test
TL;DR: The MSSA and MRSA strains adhered on an abiotic surface and formed a biofilm at distinct rates and with different sensitivities to ions, confirming the utility as well as the limits of the BFRT?
Journal ArticleDOI
Bacterial association and oral biofilm formation: A bibliometric analysis
Luana Kelle Batist Moura,FabrÃcio Ibiapina Tapety,Mitra Mobim,Eliana Campêlo Lago,Eduardo Souza de Lobão Veras,Carla Maria de Carvalho Leite Leal Nunes,Tanit Clementino Santos,Thiago Lima Monte +7 more
TL;DR: The descriptive analysis of the main work has shown potential for the development of the area and contributions to improve the prevention and treatment of oral biofilms and the relationship between the most important articles shows that the issue is addressed in a broad and diversified approach.
Journal ArticleDOI
Patient's cells colonize the biofilm of Tenckhoff catheters used in peritoneal dialysis.
TL;DR: It was concluded that the presence of a biofilm is not necessarily related with peritonitis, and biofilm features may correlate to the therapy time.
Journal ArticleDOI
Metagenomic insights into taxonomic, functional diversity and inhibitors of microbial biofilms.
Madangchanok Imchen,V. T. Anju,Siddhardha Busi,Mahima S Mohan,Pattnaik Subhaswaraj,Madhu Dyavaiah,Ranjith Kumavath +6 more
TL;DR: In this paper , a review article explores the biofilm microbiome in built and natural settings such as agriculture, household appliances, wastewater treatment plants, hospitals, microplastics, and dental biofilm.
Book ChapterDOI
The Role of Biofilms in Upper Respiratory Tract Infections
Sara Torretta,Lorenzo Pignataro +1 more
TL;DR: New insights into biofilm-related upper respiratory tract infections are reviewed and possible therapies are discussed to discuss possible therapies.
References
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Journal ArticleDOI
Bacterial biofilms : A common cause of persistent infections
TL;DR: Improvements in understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.
Journal ArticleDOI
Neutrophil extracellular traps kill bacteria
Volker Brinkmann,Ulrike Reichard,Christian Goosmann,Beatrix Fauler,Yvonne Uhlemann,David S. Weiss,Yvette Weinrauch,Yvette Weinrauch,Arturo Zychlinsky +8 more
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Journal ArticleDOI
Bacterial biofilms: from the natural environment to infectious diseases.
TL;DR: It is evident that biofilm formation is an ancient and integral component of the prokaryotic life cycle, and is a key factor for survival in diverse environments.
Journal ArticleDOI
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
TL;DR: It is understood that biofilms are universal, occurring in aquatic and industrial water systems as well as a large number of environments and medical devices relevant for public health, and that treatments may be based on inhibition of genes involved in cell attachment and biofilm formation.
Journal ArticleDOI
Antibiotic resistance of bacteria in biofilms
TL;DR: The features of biofilm infections are summarized, the emerging mechanisms of resistance are reviewed, and potential therapies are discussed.