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Fine-needle aspiration of the thyroid: an overview

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TLDR
Fine needle aspiration of the thyroid now is practiced worldwide and proves to be the most economical and reliable diagnostic procedure to identify TNs that need surgical excision andTNs that can be managed conservatively.
Abstract
Thyroid nodules (TN) are a common clinical problem. Fine needle aspiration (FNA) of the thyroid now is practiced worldwide and proves to be the most economical and reliable diagnostic procedure to identify TNs that need surgical excision and TNs that can be managed conservatively. The key for the success of thyroid FNA consists of an adequate or representative cell sample and the expertise in thyroid cytology. The FNA cytologic manifestations of TNs may be classified into seven working cytodiagnostic groups consisting of a few heterogenous lesions each to facilitate the differential diagnosis. Recent application of diagnostic molecular techniques to aspirated thyroid cells proved to be useful in separating benign from malignant TNs in several cases of indeterminate lesions.

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Citations
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Journal ArticleDOI

The National Cancer Institute Thyroid fine needle aspiration state of the science conference: a summation

TL;DR: The two-day "live" conference in October, attended by 154 registrants, gave the committees an in-depth opportunity to present their conclusions and debate controversial areas, and the establishment of an on-line educational cytopathology atlas.
Journal ArticleDOI

Fine-needle aspiration of follicular lesions of the thyroid. Diagnosis and follow-Up

TL;DR: It is important to divide follicular patterned lesions of thyroid into FON and FDN in the cytology specimens due to significantly different risk of malignancy, and clinical features, including gender and age can be part of the decision analysis in selecting patients for surgery.
Journal ArticleDOI

Evidence-based evaluation of the risks of malignancy predicted by thyroid fine-needle aspiration biopsies.

TL;DR: The evidence levels of the data used by NCI to predict malignancy risks and whether those estimates had clinical validity in the patient population were evaluated.
Journal ArticleDOI

How important is on‐site adequacy assessment for thyroid FNA? An evaluation of 883 cases

TL;DR: Evaluated the nondiagnostic rates (NDR) with and without the IADA forthyroid aspirates, and evaluated the number of passes performed in each FNA to determine the optimal number.
References
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Journal ArticleDOI

Management of a Solitary Thyroid Nodule

TL;DR: This review describes a strategy for the treatment of clinically euthyroid patients who have a solitary thyroid nodule that prevents unnecessary testing while identifying the few patients who require therapy.
Journal ArticleDOI

Fine-Needle Aspiration Biopsy of the Thyroid: An Appraisal

TL;DR: The utility and limitations of fine-needle aspiration biopsy in the evaluation and management of thyroid nodules are examined by reviewing studies reported in the literature from 1982 to 1991 and using 12 years of experience with more than 11 000 biopsies to offer a reasoned approach to the management of nodular thyroid disease.
Book

Sternberg's Diagnostic Surgical Pathology

TL;DR: Sternberg's diagnostic surgical pathology is a treatment for central giant cell granuloma and its role in traditional and innovative surgical procedures is still under debate.
Journal ArticleDOI

Diagnostic Accuracy of Conventional Versus Sonography-Guided Fine-Needle Aspiration Biopsy of Thyroid Nodules

TL;DR: It is demonstrated that SG-FNAB allows a more precise and adequate sampling of thyroid nodular lesions and is associated with a lower rate of false-negatives, thus improving global diagnostic accuracy in the preoperative selection of thyroid cancer.
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