Journal ArticleDOI
Food allergy: riding the second wave of the allergy epidemic.
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TLDR
This data indicates that children with a history of food allergy are more likely to be at risk of developing anaphylactic shock than those who do not have an allergy.Abstract:
Food allergy is a substantial and evolving public health issue, recently emerging over the last 10-15 yr as a 'second wave' of the allergy epidemic. It remains unclear why this new phenomenon has lagged decades behind the 'first wave' of asthma, allergic rhinitis and inhalant sensitization. In regions like Australia, which lead the respiratory epidemic, challenge-proven IgE-mediated food allergy now affects up to 10% of infants. Although their parents were among the first generation to experience the large-scale rise in allergic diseases, disorders of oral tolerance were previously uncommon. Of further concern, this new generation appears less likely to outgrow food allergy than their predecessors with long-term implications for disease burden. Allergic disease has been linked to the modern lifestyle including changing dietary patterns, changing intestinal commensal bacteria and vehicular pollution. It is not yet known whether the rise in food allergy is a harbinger of earlier and more severe effects of these progressive environmental changes or whether additional or unrelated lifestyle factors are implicated. New studies suggest environmental factors can produce epigenetic changes in gene expression and disease risk that may be potentially heritable across generations. The rising rates of maternal allergy, a strong direct determinant of allergic risk, could also be amplifying the effect of environmental changes. Preliminary evidence that non-Caucasian populations may be even more susceptible to the adverse effects of 'westernisation' has substantial global implications with progressive urbanization of the more populous regions in the developing world. Unravelling the environmental drivers is critical to curtail a potential tsunami of allergic disease.read more
Citations
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Journal ArticleDOI
Prevalence of common food allergies in Europe: a systematic review and meta‐analysis
Bright I Nwaru,Bright I Nwaru,L. Hickstein,Sukhmeet S Panesar,Graham Roberts,Graham Roberts,Antonella Muraro,Aziz Sheikh,Aziz Sheikh,Aziz Sheikh +9 more
TL;DR: The lifetime self‐reported prevalence of allergy to common foods in Europe ranged from 0.1 to 6.0%.
Journal ArticleDOI
A global survey of changing patterns of food allergy burden in children.
Susan L. Prescott,Ruby Pawankar,Ruby Pawankar,Ruby Pawankar,Katrina J. Allen,Katrina J. Allen,Katrina J. Allen,Dianne E. Campbell,Dianne E. Campbell,John Sinn,John Sinn,Alessandro Fiocchi,Motohiro Ebisawa,Hugh A. Sampson,Kirsten Beyer,Bee Wah Lee +15 more
TL;DR: There remains a need to gather more accurate data on the prevalence of food allergy in many developed and developing countries to better anticipate and address the rising community and health service burden of food allergies.
Journal ArticleDOI
The epidemiology of food allergy in Europe: a systematic review and meta‐analysis
Bright I Nwaru,L. Hickstein,Sukhmeet S Panesar,Antonella Muraro,Thomas Werfel,Victoria Cardona,Anthony E.J. Dubois,Susanne Halken,Karin Hoffmann-Sommergruber,Lars K. Poulsen,Graham Roberts,Graham Roberts,Graham Roberts,R. van Ree,Berber Vlieg-Boerstra,Aziz Sheikh,Aziz Sheikh +16 more
TL;DR: While the incidence of FA appeared stable over time, there was some evidence that the prevalence may be increasing, and sex, age, country of residence, familial atopic history, and the presence of other allergic diseases seem to be important.
Journal ArticleDOI
Breastfeeding and asthma and allergies: a systematic review and meta‐analysis
Caroline J Lodge,Caroline J Lodge,Daniel J Tan,Daniel J Tan,Melisa Y. Z. Lau,Xiaochen Dai,Rachel Tham,Adrian J. Lowe,Adrian J. Lowe,Gayan Bowatte,Katrina J. Allen,Katrina J. Allen,Shyamali C. Dharmage,Shyamali C. Dharmage +13 more
TL;DR: To systematically review the association between breastfeeding and childhood allergic disease, a large number of studies have concluded that breastfeeding and allergic disease are linked.
Breastfeeding and asthma and allergies: a systematic review and
Daniel J Tan,Mxz Lau,Xiaochen Dai,Rachel Tham,Adrian J. Lowe,Gayan Bowatte,Katrina J. Allen,Shyamali C. Dharmage,Caroline J Lodge +8 more
TL;DR: In this article, the association between breastfeeding and childhood allergic disease was systematically reviewed and a meta-regression was performed for categories of breastfeeding and allergic outcomes, including asthma and allergic rhinitis.
References
More filters
Journal ArticleDOI
Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys
M. Innes Asher,Stephen Montefort,Bengt Björkstén,Christopher K.W. Lai,David P. Strachan,Stephan K. Weiland,Hywel C Williams +6 more
TL;DR: The rise in prevalence of symptoms in many centres is concerning, but the absence of increases in prevalence in asthma symptoms for centres with existing high prevalence in the older age-group is reassuring.
Journal ArticleDOI
The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases
TL;DR: This review examines the evidence in support of the hygiene hypothesis and offers a number of mechanisms that could explain the relation between sanitary conditions and susceptibility to allergic and autoimmune diseases.
Journal ArticleDOI
Epigenetics: A Landscape Takes Shape
TL;DR: The epistemology of epigenetics is examined, a brief overview of underlying molecular mechanisms is provided, and future challenges for the field are suggested.
Journal ArticleDOI
Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC)
Neil Pearce,Nadia Aït-Khaled,Richard Beasley,Javier Mallol,Ulrich Keil,Ed A. Mitchell,Colin F. Robertson +6 more
TL;DR: Findings indicate that international differences in asthma symptom prevalence have reduced, particularly in the 13–14 year age group, with decreases in prevalence in English speaking countries and Western Europe and increases inPrevalence in regions where prevalence was previously low.
Journal ArticleDOI
Family size, infection and atopy: the first decade of the "hygiene hypothesis".
TL;DR: Changes in family size over the last 30 years do not appear to explain much of the reported increase in asthma or hay fever prevalence.
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