FRAX™ and the assessment of fracture probability in men and women from the UK
TLDR
The models provide a framework which enhances the assessment of fracture risk in both men and women by the integration of clinical risk factors alone and/or in combination with BMD.Abstract:
Summary
A fracture risk assessment tool (FRAX™) is developed based on the use of clinical risk factors with or without bone mineral density tests applied to the UK.read more
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Sipuleucel-T immunotherapy for castration-resistant prostate cancer.
Philip W. Kantoff,Celestia S. Higano,N. Shore,E. Roy Berger,Eric J. Small,David F. Penson,Charles H. Redfern,Anna C. Ferrari,Robert Dreicer,Robert B. Sims,Yi Xu,Mark W. Frohlich,Paul F. Schellhammer +12 more
TL;DR: The use of sipuleucel-T prolonged overall survival among men with metastatic castration-resistant prostate cancer and immune responses to the immunizing antigen were observed in patients who received sipuleUcel- T.
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Clinician’s Guide to Prevention and Treatment of Osteoporosis
Felicia Cosman,S. J. de Beur,Meryl S. LeBoff,E. M. Lewiecki,B. Tanner,S. Randall,Robert Lindsay +6 more
TL;DR: The Clinician’s Guide to Prevention and Treatment of Osteoporosis was developed by an expert committee of the National Osteiporosis Foundation in collaboration with a multispecialty council of medical experts in the field of bone health convened by NOF.
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European guidance for the diagnosis and management of osteoporosis in postmenopausal women
John A. Kanis,Eugene V. McCloskey,Helena Johansson,Cyrus Cooper,René Rizzoli,Jean-Yves Reginster +5 more
TL;DR: In this paper, the European Foundation for Osteoporosis and Bone disease (subsequently the International osteopo- rosis Foundation) published guidelines for the diagnosis and management of osteoporrosis in a European setting.
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Guidelines for the management of thyroid cancer
Petros Perros,Kristien Boelaert,Steve Colley,Carol Evans,Rhordi M Evans,Georgina Gerrard Ba,Jackie Gilbert,Barney Harrison,Sarah J. Johnson,T. Giles,Laura Moss,Val Lewington,Kate Newbold,Judith Taylor,Rajesh V. Thakker,John Watkinson,Graham R. Williams +16 more
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The Assessment of Fracture Risk
TL;DR: An approach combining the assessment of bone mineral density, clinical risk factors for fracture with use of the FRAX, and bone turnover markers will improve the prediction of fracture risk and enhance the evaluation of patients with osteoporosis.
References
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Statistical Methods in Cancer Research
TL;DR: Statistical methods in cancer research as mentioned in this paper, Statistical Methods in Cancer Research, Statistical methods in Cancer research, Statistical methods for cancer research, کتابخانه مرکزی دانشگاه علوم پزش
Journal ArticleDOI
Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project
S. Sans,Alessandro Menotti,G. De Backer,Dirk De Bacquer,P. Jousilahti,U Keil,Inger Njølstad,T. Thomsen,Hugh Tunstall-Pedoe,Aage Tverdal,Hans Wedel,Lars Wilhelmsen,I. M. Graham +12 more
TL;DR: The SCORE risk estimation system offers direct estimation of total fatal cardiovascular risk in a format suited to the constraints of clinical practice.
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Statistical methods in cancer research
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Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures
TL;DR: Measurements of bone mineral density can predict fracture risk but cannot identify individuals who will have a fracture, and a programme of screening menopausal women for osteoporosis by measuring bone density cannot be recommended.
Assessment of fracture risk and its application to screening for postmenopausal osteoporos
L. Alexeeva,P. Burkhardt,C. Christiansen,C. Cooper,P. Delmas,O. Johnell,C. Johnston,J. Kanis,P. Lips,Lee J. Melton,P. Meunier,Ego Seeman,J. Stepan,A. Tosteson,N. Khaltaev,J. P. Bonjour,H. Gong-Yi,R. Lindsay +17 more
TL;DR: There is little evidence that osteoporosis can usefully be tackled by a public health policy to influence risk factors such as smoking, exercise and nutrition, so the selective use of screening techniques will improve the cost-benefit ratio of intervention.