Glutathione in plants: biosynthesis and physiological role in environmental stress tolerance
TLDR
In this review, the recent progress in GSH biosynthesis, metabolism and its role in abiotic stress tolerance is discussed.Abstract:
Glutathione (GSH; γ-glutamyl-cysteinyl-glycine) is a small intracellular thiol molecule which is considered as a strong non-enzymatic antioxidant. Glutathione regulates multiple metabolic functions; for example, it protects membranes by maintaining the reduced state of both α-tocopherol and zeaxanthin, it prevents the oxidative denaturation of proteins under stress conditions by protecting their thiol groups, and it serves as a substrate for both glutathione peroxidase and glutathione S-transferase. By acting as a precursor of phytochelatins, GSH helps in the chelating of toxic metals/metalloids which are then transported and sequestered in the vacuole. The glyoxalase pathway (consisting of glyoxalase I and glyoxalase II enzymes) for detoxification of methylglyoxal, a cytotoxic molecule, also requires GSH in the first reaction step. For these reasons, much attention has recently been directed to elucidation of the role of this molecule in conferring tolerance to abiotic stress. Recently, this molecule has drawn much attention because of its interaction with other signaling molecules and phytohormones. In this review, we have discussed the recent progress in GSH biosynthesis, metabolism and its role in abiotic stress tolerance.read more
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Reactive Oxygen Species and Antioxidant Defense in Plants under Abiotic Stress: Revisiting the Crucial Role of a Universal Defense Regulator
Mirza Hasanuzzaman,M. H. M. Borhannuddin Bhuyan,Faisal Zulfiqar,Ali Raza,Sayed Mohammad Mohsin,Sayed Mohammad Mohsin,Jubayer Al Mahmud,Masayuki Fujita,Vasileios Fotopoulos +8 more
TL;DR: This review has documented the recent advancement illustrating the harmful effects of ROS, antioxidant defense system involved in ROS detoxification under different abiotic stresses, and molecular cross-talk with other important signal molecules such as reactive nitrogen, sulfur, and carbonyl species.
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Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases.
Mehdi Sharifi-Rad,Nanjangud V. Anil Kumar,Paolo Zucca,Elena Maria Varoni,Luciana Dini,Elisa Panzarini,Jovana Rajkovic,Patrick Valere Tsouh Fokou,Elena Azzini,Ilaria Peluso,Abhay Prakash Mishra,Manisha Nigam,Youssef El Rayess,Marc El Beyrouthy,Letizia Polito,Marcello Iriti,Natália Martins,Miquel Martorell,Anca Oana Docea,William N. Setzer,Daniela Calina,William C. Cho,Javad Sharifi-Rad +22 more
TL;DR: The diseases in which oxidative stress is one of the triggers and the plant-derived antioxidant compounds with their mechanisms of antioxidant defenses that can help in the prevention of these diseases are discussed.
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Regulation of Ascorbate-Glutathione Pathway in Mitigating Oxidative Damage in Plants under Abiotic Stress
Mirza Hasanuzzaman,M. H. M. Borhannuddin Bhuyan,M. H. M. Borhannuddin Bhuyan,Taufika Islam Anee,Khursheda Parvin,Khursheda Parvin,Kamrun Nahar,Jubayer Al Mahmud,Masayuki Fujita +8 more
TL;DR: This review summarizes the recent progress of the research on AsA-GSH pathway in terms of oxidative stress tolerance in plants and focuses on the defense mechanisms as well as molecular interactions.
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The effect of developmental and environmental factors on secondary metabolites in medicinal plants.
TL;DR: The results of these reviews can know how developmental and environmental factors qualitatively and quantitatively influence SMs of medicinal plants and how these can be integrated as tools to quality control, as well as on the improvement of clinical curative effects by altering their genomes, and/or growth conditions.
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Friend or foe? Reactive oxygen species production, scavenging and signaling in plant response to environmental stresses.
TL;DR: Over the past two decades it has been proven that ROS together with non‐photochemical quenching (NPQ), hormones, Ca2+ waves, and electrical signals are the main players in SAA and SAR, two physiological processes essential for plant survival and productivity in unfavorable conditions.
References
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