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Open AccessJournal ArticleDOI

Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice.

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TLDR
The present work demonstrates the feasibility of in vivo PPTT treatment of deep-tissue malignancies using easily-prepared plasmonic gold nanorods and a small, portable, inexpensive near-infrared (NIR) laser.
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This article is published in Cancer Letters.The article was published on 2008-09-28 and is currently open access. It has received 1097 citations till now. The article focuses on the topics: Photothermal therapy.

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The golden age: gold nanoparticles for biomedicine

TL;DR: It is argued that gold nanotechnology-enabled biomedicine is not simply an act of 'gilding the (nanomedicinal) lily', but that a new 'Golden Age' of biomedical nanotechnology is truly upon us.
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Ultrasmall Reduced Graphene Oxide with High Near-Infrared Absorbance for Photothermal Therapy

TL;DR: Nano-rGO is established as a novel photothermal agent due to its small size, high photothermal efficiency, and low cost as compared to other NIR photothermal agents including gold nanomaterials and carbon nanotubes.
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Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications

TL;DR: Of all the possible nanoparticle shapes, gold nanorods are especially intriguing as they offer strong plasmonic fields while exhibiting excellent tunability and biocompatibility, according to a review of their radiative and nonradiative properties.
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Gold nanoparticles: Optical properties and implementations in cancer diagnosis and photothermal therapy

TL;DR: The surface plasmon resonance of gold nanoparticles leads to strong electromagnetic fields on the particle surface and consequently enhances all the radiative properties such as absorption and scattering as discussed by the authors, and the strongly absorbed light is converted to heat quickly via a series of nonradiative processes.
References
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Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology.

TL;DR: A review of gold nanoparticles can be found in this article, where the most stable metal nanoparticles, called gold colloids (AuNPs), have been used for catalysis and biology applications.
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Chemistry and properties of nanocrystals of different shapes.

TL;DR: The interest in nanoscale materials stems from the fact that new properties are acquired at this length scale and, equally important, that these properties are equally important.
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Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods

TL;DR: It is found that, after exposure to continuous red laser at 800 nm, malignant cells require about half the laser energy to be photothermally destroyed than the nonmalignant cells, so both efficient cancer cell diagnostics and selective photothermal therapy are realized at the same time.
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Photodynamic therapy for cancer

TL;DR: PDT is being tested in the clinic for use in oncology — to treat cancers of the head and neck, brain, lung, pancreas, intraperitoneal cavity, breast, prostate and skin.
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