Salivary pH: A diagnostic biomarker.
TLDR
The salivary pH shows significant changes and thus relevance to the severity of periodontal disease and may be used as a quick chairside diagnostic biomarker.Abstract:
Objectives: Saliva contains a variety of host defense factors It influences calculus formation and periodontal disease Different studies have been done to find exact correlation of salivary biomarkers with periodontal disease With a multitude of biomarkers and complexities in their determination, the salivary pH may be tried to be used as a quick chairside test The aim of this study was to analyze the pH of saliva and determine its relevance to the severity of periodontal disease Study Design: The study population consisted of 300 patients They were divided into three groups of 100 patients each: Group A had clinically healthy gingiva, Group B who had generalized chronic gingivitis and Group C who had generalized chronic periodontitis The randomized unstimulated saliva from each patient was collected and pH was tested Data was analyzed statistically using analysis of variance technique Results: The salivary pH was more alkaline for patients with generalized chronic gingivitis as compared with the control group ( P = 0001) whereas patients with generalized chronic periodontitis had more acidic pH as compared with the control group ( P = 0001) Conclusion: These results indicate a significant change in the pH depending on the severity of the periodontal condition The salivary pH shows significant changes and thus relevance to the severity of periodontal disease Salivary pH may thus be used as a quick chairside diagnostic biomarkerread more
Citations
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References
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TL;DR: Current data suggest that pathogens are necessary but not sufficient for disease activity to occur, and the local environment of the periodontal pocket may be important in the regulation of expression of virulence factors by pathogenic species.
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W. E. C. Moore,L. V. H. Moore,Richard R. Ranney,R. M. Smibert,J. A. Burmeister,Harvey A. Schenkein +5 more
TL;DR: The composition of microbiological floras of all periodontitis samples was statistically significantly different from that of subjects with healthy gingiva and that of active and control sites in AP subjects and the composition of microfloras of sites in subjects with naturally-occurring gingivitis was intermediate.
Journal ArticleDOI
Evaluation of Components of Gingival Crevicular Fluid as Diagnostic Tests
TL;DR: Gingival crevicular fluid (GCF) as mentioned in this paper is an inflammatory exudate that can be collected at the gingival margin or within the crevice and biochemical analysis of the fluid offers a noninvasive means of assessing the host response in periodontal disease.
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Detection of high‐risk groups and individuals for periodontal diseases:
Michael A. Curtis,I. R. Gillett,G. S. Griffiths,M. F. J. Maiden,J. A. C. Sterne,D. T. Wilson,J. M. A. Wilton,N. W. Johnson +7 more
TL;DR: Though gingivitis has a prevalence of close to 100 per cent in many populations, most forms of the 'disease' are self-limiting and reversible: tooth support and function are not compromised so the public health importance of the condition is questionable.
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