Journal of Indian Society of Periodontology 

About: Journal of Indian Society of Periodontology is an academic journal published by Medknow. The journal publishes majorly in the area(s): Periodontitis & Chronic periodontitis. It has an ISSN identifier of 0972-124X. It is also open access. Over the lifetime, 1414 publications have been published receiving 16604 citations.

Salivary pH: A diagnostic biomarker.

Abstract: Objectives: Saliva contains a variety of host defense factors It influences calculus formation and periodontal disease Different studies have been done to find exact correlation of salivary biomarkers with periodontal disease With a multitude of biomarkers and complexities in their determination, the salivary pH may be tried to be used as a quick chairside test The aim of this study was to analyze the pH of saliva and determine its relevance to the severity of periodontal disease Study Design: The study population consisted of 300 patients They were divided into three groups of 100 patients each: Group A had clinically healthy gingiva, Group B who had generalized chronic gingivitis and Group C who had generalized chronic periodontitis The randomized unstimulated saliva from each patient was collected and pH was tested Data was analyzed statistically using analysis of variance technique Results: The salivary pH was more alkaline for patients with generalized chronic gingivitis as compared with the control group ( P = 0001) whereas patients with generalized chronic periodontitis had more acidic pH as compared with the control group ( P = 0001) Conclusion: These results indicate a significant change in the pH depending on the severity of the periodontal condition The salivary pH shows significant changes and thus relevance to the severity of periodontal disease Salivary pH may thus be used as a quick chairside diagnostic biomarker

Antimicrobial photodynamic therapy: An overview

Abstract: Inflammatory periodontal disease caused by dental plaque is characterized by the clinical signs of inflammation and loss of periodontal tissue support The mechanical removal of this biofilm and adjunctive use of antibacterial disinfectants and antibiotics have been the conventional methods of periodontal therapy But the removal of plaque and the reduction in the number of infectious organisms can be impaired in sites with difficult access The possibility of development of resistance to antibiotics by the target organism has led to the development of a new antimicrobial concept with fewer complications Photodynamic therapy (PDT) involves the use of low power lasers with appropriate wavelength to kill micro organisms treated with a photosensitizer drug PDT could be a useful adjunct to mechanical as well as antibiotics in eliminating periopathogenic bacteria

Future impact of nanotechnology on medicine and dentistry.

Abstract: The human characteristics of curiosity, wonder, and ingenuity are as old as mankind. People around the world have been harnessing their curiosity into inquiry and the process of scientific methodology. Recent years have witnessed an unprecedented growth in research in the area of nanoscience. There is increasing optimism that nanotechnology applied to medicine and dentistry will bring significant advances in the diagnosis, treatment, and prevention of disease. Growing interest in the future medical applications of nanotechnology is leading to the emergence of a new field called nanomedicine. Nanomedicine needs to overcome the challenges for its application, to improve the understanding of pathophysiologic basis of disease, bring more sophisticated diagnostic opportunities, and yield more effective therapies and preventive properties. When doctors gain access to medical robots, they will be able to quickly cure most known diseases that hobble and kill people today, to rapidly repair most physical injuries our bodies can suffer, and to vastly extend the human health span. Molecular technology is destined to become the core technology underlying all of 21(st) century medicine and dentistry. In this article, we have made an attempt to have an early glimpse on future impact of nanotechnology in medicine and dentistry.

Biofilms: A microbial home.

Abstract: Microbial biofilms are mainly implicated in etiopathogenesis of caries and periodontal disease Owing to its properties, these pose great challenges Continuous and regular disruption of these biofilms is imperative for prevention and management of oral diseases This essay provides a detailed insight into properties, mechanisms of etiopathogenesis, detection and removal of these microbial biofilms

Reactive oxygen species in periodontitis

Abstract: Recent epidemiological studies reveal that more than two-third of the world's population suffers from one of the chronic forms of periodontal disease. The primary etiological agent of this inflammatory disease is a polymicrobial complex, predominantly Gram negative anaerobic or facultative bacteria within the sub-gingival biofilm. These bacterial species initiate the production of various cytokines such as interleukin-8 and TNF-α, further causing an increase in number and activity of polymorphonucleocytes (PMN) along with these cytokines, PMNs also produce reactive oxygen species (ROS) superoxide via the respiratory burst mechanism as the part of the defence response to infection. ROS just like the interleukins have deleterious effects on tissue cells when produced in excess. To counter the harmful effects of ROS, human body has its own defence mechanisms to eliminate them as soon as they are formed. The aim of this review is to focus on the role of different free radicals, ROS, and antioxidants in the pathophysiology of periodontal tissue destruction.