G
Gregory J. Zipfel
Researcher at Washington University in St. Louis
Publications - 252
Citations - 11138
Gregory J. Zipfel is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Subarachnoid hemorrhage & Vasospasm. The author has an hindex of 46, co-authored 230 publications receiving 9299 citations. Previous affiliations of Gregory J. Zipfel include University of Florida & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
The changing landscape of ischaemic brain injury mechanisms
TL;DR: From a perspective that broadening of therapeutic targeting beyond excitotoxicity and neuronal calcium overload will be desirable for developing the most effective neuroprotective therapies, intrinsic tissue mechanisms of ischaemic brain injury are discussed.
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Critical Care Management of Patients Following Aneurysmal Subarachnoid Hemorrhage: Recommendations from the Neurocritical Care Society’s Multidisciplinary Consensus Conference
Michael N. Diringer,Thomas P. Bleck,J. Claude Hemphill,David K. Menon,Lori Shutter,Paul M. Vespa,Nicolas Bruder,E. Sander Connolly,Giuseppe Citerio,Daryl R. Gress,Daniel Hänggi,Brian L. Hoh,Giuseppe Lanzino,Peter D. Le Roux,Alejandro A. Rabinstein,Erich Schmutzhard,Nino Stocchetti,Jose I. Suarez,Miriam Treggiari,Ming Yuan Tseng,Mervyn D.I. Vergouwen,Stefan Wolf,Gregory J. Zipfel +22 more
TL;DR: Recommendations were developed based on literature review using the GRADE system, discussion integrating the literature with the collective experience of the participants and critical review by an impartial jury and emphasis was placed on the principle that recommendations should be based not only on the quality of the data but also tradeoffs and translation into practice.
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Vascular contributions to cognitive impairment and dementia including Alzheimer's disease
Heather M. Snyder,Roderick A. Corriveau,Suzanne Craft,James E. Faber,Steven M. Greenberg,David S. Knopman,Bruce T. Lamb,Thomas J. Montine,Chris B. Schaffer,Julie A. Schneider,Cheryl L. Wellington,Donna M. Wilcock,Gregory J. Zipfel,Berislav V. Zlokovic,Lisa J. Bain,Francesca Bosetti,Zorina S. Galis,Walter J. Koroshetz,Maria C. Carrillo +18 more
TL;DR: A summary of the meeting and the resultant discussion of how vascular factors contribute to Alzheimer's disease and related dementia is summarized, including an outline of next steps needed to move this area of research forward.
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Brain tissue responses to ischemia
TL;DR: The role of injury-enhancing signaling mechanisms specific to the central nervous system (CNS) are emphasized and potential therapeutic approaches to interrupting these mechanisms are discussed.
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Clinical Features and Outcome in North American Adults With Moyamoya Phenomenon
Christopher L. Hallemeier,Keith M. Rich,Robert L. Grubb,Michael R. Chicoine,Christopher J. Moran,DeWitte T. Cross,Gregory J. Zipfel,Ralph G. Dacey,Colin P. Derdeyn +8 more
TL;DR: Moyamoya phenomenon in North American adults is associated with a high risk of recurrent stroke, particularly those with bilateral involvement and ischemic symptoms, and data suggest a potential benefit with surgery if diagnosis could be made earlier.