Miriam Treggiari

TL;DR: Recommendations were developed based on literature review using the GRADE system, discussion integrating the literature with the collective experience of the participants and critical review by an impartial jury and emphasis was placed on the principle that recommendations should be based not only on the quality of the data but also tradeoffs and translation into practice.

TL;DR: Prophylactic hyperdynamic therapy after subarachnoid hemorrhage has not been adequately shown to effectively raise cerebral blood flow or improve neurological outcome, and there is evidence for harm using overly aggressive hydration.

TL;DR: Outcome is influenced by patient volume, with better outcome occurring in high-volume centers treating >60 cases per year, including the availability of neurointensivists and interventional care.

TL;DR: Overall, hypertension was associated with higher cerebral blood flow, regardless of volume status (normo- or hypervolemia), with neurological symptom reversal seen in two-thirds of treated patients, and no incremental risk of aneu- rysmal rupture has been reported with the induction of hemodynamic augmentation.