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Bingwen Eugene Fan
Researcher at Tan Tock Seng Hospital
Publications - 63
Citations - 1345
Bingwen Eugene Fan is an academic researcher from Tan Tock Seng Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 30 publications receiving 739 citations. Previous affiliations of Bingwen Eugene Fan include Khoo Teck Puat Hospital.
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Journal ArticleDOI
Hematologic parameters in patients with COVID-19 infection.
Bingwen Eugene Fan,Vanessa Cui Lian Chong,Stephrene Seok Wei Chan,Gek Hsiang Lim,Kian Guan Eric Lim,Guat Bee Tan,Sharavan Sadasiv Mucheli,Ponnudurai Kuperan,Kiat Hoe Ong +8 more
TL;DR: A detailed analysis of the hematological parameters of the COVID-19 patients at the NCID revealed that a higher number of patients (69%) who were lymphopenic had the presence of a few reactive lymphocytes, of which a subset appeared lymphoplasmacytoid, which contrasts with the severe acute respiratory syndrome (SARS) outbreak in 2003 where reactive lymph cells were not observed in a study on Haematologic parameters.
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Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19.
Guillaume Carissimo,Weili Xu,Immanuel Kwok,Mohammad Yazid Abdad,Yi Hao Chan,Siew-Wai Fong,Siew-Wai Fong,Kia Joo Puan,Cheryl Yi-Pin Lee,Nicholas Kim-Wah Yeo,Siti Naqiah Amrun,Rhonda Sin-Ling Chee,Wilson How,Stephrene Seok Wei Chan,Bingwen Eugene Fan,Anand Kumar Andiappan,Bernett Lee,Olaf Rötzschke,Barnaby Edward Young,Barnaby Edward Young,Yee Sin Leo,David C. Lye,Laurent Rénia,Lai Guan Ng,Anis Larbi,Lisa F. P. Ng +25 more
TL;DR: Comprehensive flow cytometry of whole blood samples from 54 COVID-19 patients reveals a dramatic increase in the number of immature neutrophils, which strongly correlates with disease severity and is associated with elevated IL-6 and IP-10 levels, two key players in the cytokine storm.
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COVID-19 and mycoplasma pneumoniae coinfection.
Bingwen Eugene Fan,Kian Guan Eric Lim,Vanessa Cui Lian Chong,Stephrene Seok Wei Chan,Kiat Hoe Ong,Ponnudurai Kuperan +5 more
TL;DR: COVID-19 and mycoplasma pneumoniae coinfection Bingwen Eugene Fan, Vanessa Cui Lian Chong, Stephrene Seok Wei Chan, and Ponnudurai Kuperan Department of Haematology and Singapore Department of Laboratory Medicine.
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Delayed catastrophic thrombotic events in young and asymptomatic post COVID-19 patients
Bingwen Eugene Fan,Thirugnanam Umapathi,Karen Chua,Yew Woon Chia,Shiun Woei Wong,Glenn Wei Leong Tan,Sadhana Chandrasekar,Ying Hui Lum,Shawn Vasoo,Rinkoo Dalan +9 more
TL;DR: A series of catastrophic arterial events observed in post COVID-19 patients are highlighted, echoing the Editor’s concerns of post-infectious vasculopathy.
Journal ArticleDOI
Hematologic parameters in patients with COVID-19 infection: a reply.
TL;DR: The International Society for Thrombosis and Haemostasis (ISTH) interim guidance on recognition and management of coagulopathy in CO VID-19 has the recommendation that prophylactic dose low molecular weight heparin should be considered in all patients, who require hospital admission for COVID-19 infection in the absence of any contraindications.