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Stephrene Seok Wei Chan
Researcher at Tan Tock Seng Hospital
Publications - 17
Citations - 931
Stephrene Seok Wei Chan is an academic researcher from Tan Tock Seng Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 13 publications receiving 637 citations.
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Journal ArticleDOI
Hematologic parameters in patients with COVID-19 infection.
Bingwen Eugene Fan,Vanessa Cui Lian Chong,Stephrene Seok Wei Chan,Gek Hsiang Lim,Kian Guan Eric Lim,Guat Bee Tan,Sharavan Sadasiv Mucheli,Ponnudurai Kuperan,Kiat Hoe Ong +8 more
TL;DR: A detailed analysis of the hematological parameters of the COVID-19 patients at the NCID revealed that a higher number of patients (69%) who were lymphopenic had the presence of a few reactive lymphocytes, of which a subset appeared lymphoplasmacytoid, which contrasts with the severe acute respiratory syndrome (SARS) outbreak in 2003 where reactive lymph cells were not observed in a study on Haematologic parameters.
Journal ArticleDOI
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19.
Guillaume Carissimo,Weili Xu,Immanuel Kwok,Mohammad Yazid Abdad,Yi Hao Chan,Siew-Wai Fong,Siew-Wai Fong,Kia Joo Puan,Cheryl Yi-Pin Lee,Nicholas Kim-Wah Yeo,Siti Naqiah Amrun,Rhonda Sin-Ling Chee,Wilson How,Stephrene Seok Wei Chan,Bingwen Eugene Fan,Anand Kumar Andiappan,Bernett Lee,Olaf Rötzschke,Barnaby Edward Young,Barnaby Edward Young,Yee Sin Leo,David C. Lye,Laurent Rénia,Lai Guan Ng,Anis Larbi,Lisa F. P. Ng +25 more
TL;DR: Comprehensive flow cytometry of whole blood samples from 54 COVID-19 patients reveals a dramatic increase in the number of immature neutrophils, which strongly correlates with disease severity and is associated with elevated IL-6 and IP-10 levels, two key players in the cytokine storm.
Journal ArticleDOI
COVID-19 and mycoplasma pneumoniae coinfection.
Bingwen Eugene Fan,Kian Guan Eric Lim,Vanessa Cui Lian Chong,Stephrene Seok Wei Chan,Kiat Hoe Ong,Ponnudurai Kuperan +5 more
TL;DR: COVID-19 and mycoplasma pneumoniae coinfection Bingwen Eugene Fan, Vanessa Cui Lian Chong, Stephrene Seok Wei Chan, and Ponnudurai Kuperan Department of Haematology and Singapore Department of Laboratory Medicine.
Journal ArticleDOI
Blood and blood product use during COVID-19 infection.
Bingwen Eugene Fan,Kiat Hoe Ong,Stephrene Seok Wei Chan,Barnaby Edward Young,Vanessa Cui Lian Chong,Siew Ping Connie Chen,Shu Ping Lim,Geok Ping Lim,Ponnudurai Kuperan +8 more
TL;DR: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China and Elevated activated partial thromboplastin time-based clot waveform analysis markers have strong positive association with acute venous thromboembolism.
Journal ArticleDOI
COVID-19 associated coagulopathy in critically ill patients: A hypercoagulable state demonstrated by parameters of haemostasis and clot waveform analysis.
Bingwen Eugene Fan,Jensen Ng,Stephrene Seok Wei Chan,Dheepa Christopher,Allison Ching Yee Tso,Li Min Ling,Barnaby Edward Young,Lester Jun Long Wong,Christina Lai Lin Sum,Hwee Tat Tan,Mui Kia Ang,Gek Hsiang Lim,Kiat Hoe Ong,Ponnudurai Kuperan,Yew Woon Chia +14 more
TL;DR: The laboratory findings further support the view that severe SARS-CoV-2 infection is associated with a state of hypercoagulability.