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Christopher Ferrante
Researcher at Rutgers University
Publications - 8
Citations - 847
Christopher Ferrante is an academic researcher from Rutgers University. The author has contributed to research in topics: Ryanodine receptor & Calcium signaling. The author has an hindex of 7, co-authored 8 publications receiving 692 citations.
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Journal ArticleDOI
The Adenosine-Dependent Angiogenic Switch of Macrophages to an M2-Like Phenotype is Independent of Interleukin-4 Receptor Alpha (IL-4Rα) Signaling
Christopher Ferrante,Grace Pinhal-Enfield,Genie Elson,Bruce N. Cronstein,György Haskó,Shalini Outram,Samuel Leibovich +6 more
TL;DR: Adenosine signaling suppresses the TLR-dependent expression of TNF-α, IL-12, IFN-γ, and several other inflammatory cytokines by macrophages and induces the expression of vascular endothelial growth factor (VEGF) and IL-10.
Journal ArticleDOI
MG53 constitutes a primary determinant of cardiac ischemic preconditioning.
Chun-Mei Cao,Yan Zhang,Noah Weisleder,Christopher Ferrante,Xianhua Wang,Fengxiang Lv,Yi Zhang,Ruisheng Song,Moonsun Hwang,Li Jin,Jiaojiao Guo,Wei Peng,Geng Li,Miyuki Nishi,Hiroshi Takeshima,Jianjie Ma,Rui-Ping Xiao +16 more
TL;DR: MG53 is established as a primary component of the cardiac IPC response, thus identifying a potentially important novel therapeutic target for the treatment of ischemic heart disease.
Journal ArticleDOI
Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy
Noah Weisleder,Norio Takizawa,Pei-Hui Lin,Xianhua Wang,Chun-Mei Cao,Yan Zhang,Tao Tan,Christopher Ferrante,Hua Zhu,Pin-Jung Chen,Rosalie Yan,Matthew Sterling,Xiaoli Zhao,Moonsun Hwang,Miyuki Takeshima,Chuanxi Cai,Heping Cheng,Hiroshi Takeshima,Rui-Ping Xiao,Jianjie Ma +19 more
TL;DR: The data support the concept of targeted cell membrane repair in regenerative medicine, and present MG53 protein as an attractive biological reagent for restoration of membrane repair defects in human diseases.
Journal ArticleDOI
TRIC channels are essential for Ca2+ handling in intracellular stores.
Masayuki Yazawa,Christopher Ferrante,Jue Feng,Kazuhiro Mio,Toshihiko Ogura,Toshihiko Ogura,Miao Zhang,Miao Zhang,Pei-Hui Lin,Zui Pan,Shinji Komazaki,Kazuhiro Kato,Miyuki Nishi,Miyuki Nishi,Xiaoli Zhao,Noah Weisleder,Chikara Sato,Jianjie Ma,Hiroshi Takeshima,Hiroshi Takeshima +19 more
TL;DR: Two TRIC (trimeric intracellular cation) channel subtypes are reported that are differentially expressed on intrACEllular stores in animal cell types and are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intrace cellular stores.
Journal ArticleDOI
The Presenilin-2 Loop Peptide Perturbs Intracellular Ca2+ Homeostasis and Accelerates Apoptosis
Chuanxi Cai,Pei-Hui Lin,King-Ho Cheung,Na Li,Christina Levchook,Zui Pan,Christopher Ferrante,Gabrielle L. Boulianne,J. Kevin Foskett,David Danielpour,Jianjie Ma +10 more
TL;DR: It is shown that PS2-LP is a potent inducer of the mitochondrial-dependent cell death pathway when transduced as a fusion protein with HIV-TAT and biochemical and functional studies demonstrate that TAT-PS2- LP can interact with the inositol 1,4,5-trisphosphate receptor and activate Ca2+ release from the endoplasmic reticulum.