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Hua Zhu

Researcher at The Ohio State University Wexner Medical Center

Publications -  158
Citations -  11441

Hua Zhu is an academic researcher from The Ohio State University Wexner Medical Center. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 34, co-authored 134 publications receiving 9028 citations. Previous affiliations of Hua Zhu include Rutgers University & Chinese Academy of Sciences.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells.

Hua Zhu, +6 more
- 01 Sep 2008 - 
TL;DR: The results demonstrate for the first time the roles of microRNAs in the regulation of drug resistance mediated by MDR1/P-glycoprotein, and suggest the potential for targeting miR-27a and mi-451 as a therapeutic strategy for modulating MDR in cancer cells.
Journal ArticleDOI

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells

Hua Zhu, +7 more
- 16 Aug 2009 - 
TL;DR: It is reported here that microRNAs (miRNAs), a class of endogenous, 22–24 nucleotide noncoding RNA molecules able to affect stability and translation of mRNA, may represent a previously unrecognized mechanism for regulating beclin 1 expression and autophagy.
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CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice

Li Xu, +8 more
- 01 Mar 2016 - 
TL;DR: It is demonstrated that CRIPSR-mediated genome editing efficiently excised a 23-kb genomic region on the X-chromosome covering the mutant exon 23 in a mouse model of DMD, and restored dystrophin expression and the dyStrophin-glycoprotein complex at the sarcolemma of skeletal muscles in live mdx mice.