Gunilla Einecke

TL;DR: Emerging research data led to the establishment of collaborative working groups addressing issues like isolated ‘v’ lesion and incorporation of omics‐technologies, paving the way for future combination of graft biopsy and molecular parameters within the Banff process.

TL;DR: The major cause of late kidney transplant failure is antibody‐mediated microcirculation injury, but detection of this phenotype requires new diagnostic criteria.

TL;DR: It is concluded that GSEA has important limitations as a gene-set analysis approach for microarray experiments for identifying biological pathways associated with a binary phenotype and an alternative statistically-sound method is proposed, SAM-GS.

TL;DR: Many transcriptome changes previously described in rejection are features of a large‐scale disturbance characteristic of rejection but occurring at lower levels in many forms of injury, indicating that transcriptome disturbances in renal transplants have a stereotyped internal structure.

TL;DR: The molecular risk score reflects active injury and is superior to either scarring or function in predicting graft failure and was the only predictor of graft loss in an independent validation set.