K
Konrad S. Famulski
Researcher at University of Alberta
Publications - 66
Citations - 5656
Konrad S. Famulski is an academic researcher from University of Alberta. The author has contributed to research in topics: Transplantation & T cell. The author has an hindex of 37, co-authored 65 publications receiving 4825 citations.
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Journal ArticleDOI
Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence.
Joana Sellarés,D. G. de Freitas,Michael Mengel,Jeff Reeve,Gunilla Einecke,Banu Sis,Luis G. Hidalgo,Konrad S. Famulski,Arthur J. Matas,Philip F. Halloran +9 more
TL;DR: This prospective cohort indicates that many actual failures after indication biopsies manifest phenotypic features of antibody‐mediated or mixed rejection and also underscores the major role of nonadherence.
Journal ArticleDOI
Modulation of gene expression by calreticulin binding to the glucocorticoid receptor
Kimberly Burns,B Duggan,E A Atkinson,Konrad S. Famulski,Mona Nemer,R C Bleackley,Marek Michalak +6 more
TL;DR: Results indicate that calreticulin may be important in gene transcription, regulating the glucocorticoid receptor and perhaps other members of the super-family of nuclear receptors.
Journal ArticleDOI
Improving gene set analysis of microarray data by SAM-GS
Irina Dinu,John D. Potter,Thomas F. Mueller,Qi Liu,Adeniyi J. Adewale,Gian S. Jhangri,Gunilla Einecke,Konrad S. Famulski,Philip F. Halloran,Yutaka Yasui +9 more
TL;DR: It is concluded that GSEA has important limitations as a gene-set analysis approach for microarray experiments for identifying biological pathways associated with a binary phenotype and an alternative statistically-sound method is proposed, SAM-GS.
Journal ArticleDOI
Molecular diagnosis of antibody-mediated rejection in human kidney transplants.
Joana Sellarés,Jeff Reeve,Alexandre Loupy,Michael Mengel,Banu Sis,Alison Skene,D. G. de Freitas,Chatchai Kreepala,Luis G. Hidalgo,Konrad S. Famulski,Philip F. Halloran +10 more
TL;DR: It is concluded that microarray assessment of gene expression can assign a probability of ABMR to transplant biopsies without knowledge of HLA antibody status, histology, or C4d staining, and predicts future failure.
Journal ArticleDOI
Molecular diagnosis of T cell-mediated rejection in human kidney transplant biopsies.
Jeff Reeve,Joana Sellarés,Michael Mengel,Banu Sis,A. Skene,Luis G. Hidalgo,D. G. de Freitas,Konrad S. Famulski,Philip F. Halloran +8 more
TL;DR: A molecular test for T cell‐mediated rejection is developed and new rules to integrate molecular tests and histology into a precision diagnostic system that can reduce errors, ambiguity and interpathologist disagreement are proposed.