H
Hirotada Mori
Researcher at Nara Institute of Science and Technology
Publications - 187
Citations - 25374
Hirotada Mori is an academic researcher from Nara Institute of Science and Technology. The author has contributed to research in topics: Gene & Escherichia coli. The author has an hindex of 64, co-authored 185 publications receiving 23059 citations. Previous affiliations of Hirotada Mori include Kyoto University & Kumamoto University.
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Journal ArticleDOI
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection.
Tomoya Baba,Takeshi Ara,Miki Hasegawa,Yuki Takai,Yoshiko Okumura,Miki Baba,Kirill A. Datsenko,Masaru Tomita,Barry L. Wanner,Hirotada Mori,Hirotada Mori +10 more
TL;DR: These mutants—the ‘Keio collection’—provide a new resource not only for systematic analyses of unknown gene functions and gene regulatory networks but also for genome‐wide testing of mutational effects in a common strain background, E. coli K‐12 BW25113.
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Complete set of ORF clones of Escherichia coli ASKA library (A Complete Set of E. coli K-12 ORF Archive): Unique Resources for Biological Research
Masanari Kitagawa,Takeshi Ara,Mohammad Arifuzzaman,Tomoko Ioka-Nakamichi,Eiji Inamoto,Hiromi Toyonaga,Hirotada Mori +6 more
TL;DR: A complete set of cloned individual genes encoding Histidine-tagged proteins with or without GFP fused for functional genomic analysis of Escherichia coli K-12 strain should provide unique resources for systematic functional genomic approaches.
Journal ArticleDOI
Extensive impact of non-antibiotic drugs on human gut bacteria
Lisa A. Maier,Mihaela Pruteanu,Michael Kuhn,Georg Zeller,Anja Telzerow,Exene Erin Anderson,Ana Rita Brochado,Keith C. Fernandez,Hitomi Dose,Hirotada Mori,Kiran Raosaheb Patil,Peer Bork,Athanasios Typas +12 more
TL;DR: For example, this paper screened more than 1,000 marketed drugs against 40 representative gut bacterial strains, and found that 24% of the drugs with human targets, including members of all therapeutic classes, inhibited the growth of at least one strain in vitro.
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Multiple high-throughput analyses monitor the response of E. coli to perturbations.
Nobuyoshi Ishii,Kenji Nakahigashi,Tomoya Baba,Tomoya Baba,Martin Robert,Tomoyoshi Soga,Akio Kanai,Takashi Hirasawa,Miki Naba,Kenta Hirai,Aminul Hoque,Pei Yee Ho,Yuji Kakazu,Kaori Sugawara,Saori Igarashi,Satoshi Harada,Takeshi Masuda,Naoyuki Sugiyama,Takashi Togashi,Miki Hasegawa,Yuki Takai,Katsuyuki Yugi,Kazuharu Arakawa,Nayuta Iwata,Yoshihiro Toya,Yoichi Nakayama,Takaaki Nishioka,Takaaki Nishioka,Kazuyuki Shimizu,Kazuyuki Shimizu,Hirotada Mori,Hirotada Mori,Masaru Tomita +32 more
TL;DR: E. coli seems to use complementary strategies that result in a metabolic network robust against perturbations, and actively regulated enzyme levels to maintain a stable metabolic state in response to changes in growth rate.
Journal ArticleDOI
Escherichia coli K-12: a cooperatively developed annotation snapshot—2005
Monica Riley,Takashi Abe,Martha B. Arnaud,Mary B. Berlyn,Frederick R. Blattner,Roy R. Chaudhuri,Jeremy D. Glasner,Takashi Horiuchi,Ingrid M. Keseler,Takehide Kosuge,Hirotada Mori,Hirotada Mori,Nicole T. Perna,Guy Plunkett,Kenneth E. Rudd,Margrethe H. Serres,Gavin H. Thomas,Nicholas R. Thomson,David S. Wishart,Barry L. Wanner +19 more
TL;DR: A snapshot analysis based on the most recent genome sequences of two E.coli K-12 strains allows comparison of their genotypes and mutant status of alleles.