J
Jan Kluytmans
Researcher at Utrecht University
Publications - 364
Citations - 27157
Jan Kluytmans is an academic researcher from Utrecht University. The author has contributed to research in topics: Methicillin-resistant Staphylococcus aureus & Medicine. The author has an hindex of 70, co-authored 335 publications receiving 22424 citations. Previous affiliations of Jan Kluytmans include Oklahoma State University Center for Health Sciences & VU University Amsterdam.
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Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis.
Evelina Tacconelli,Elena Carrara,Alessia Savoldi,Stéphan Juergen Harbarth,Marc Mendelson,Dominique L Monnet,Céline Pulcini,Gunnar Kahlmeter,Jan Kluytmans,Yehuda Carmeli,Marc Ouellette,Kevin Outterson,Jean B. Patel,Marco Cavaleri,Edward Cox,Christopher R. Houchens,M Lindsay Grayson,Paul Hansen,Nalini Singh,Ursula Theuretzbacher,Nicola Magrini,Aaron O. Aboderin,Seif Al-Abri,Nordiah Awang Jalil,Nur Benzonana,Sanjay Bhattacharya,Adrian Brink,Francesco Robert Burkert,Otto Cars,Giuseppe Cornaglia,Oliver J. Dyar,Alexander W. Friedrich,Ana Cristina Gales,Sumanth Gandra,Christian G. Giske,Debra A. Goff,Herman Goossens,Thomas Gottlieb,Manuel Guzman Blanco,Waleria Hryniewicz,Deepthi Kattula,Timothy Jinks,Souha S. Kanj,Lawrence Kerr,Marie-Paule Kieny,Yang Soo Kim,Roman S. Kozlov,Jaime Labarca,Ramanan Laxminarayan,Karin Leder,Leonard Leibovici,Gabriel Levy-Hara,Jasper Littman,Surbhi Malhotra-Kumar,Vikas Manchanda,Lorenzo Moja,Babacar Ndoye,Angelo Pan,David L. Paterson,Mical Paul,Haibo Qiu,Pilar Ramon-Pardo,Jesús Rodríguez-Baño,Maurizio Sanguinetti,Sharmila Sengupta,Mike Sharland,Massinissa Si-Mehand,Lynn L. Silver,Wonkeung Song,Martin Steinbakk,Jens Thomsen,Guy E. Thwaites,Jos W. M. van der Meer,Nguyen Van Kinh,Silvio Vega,Maria Virginia Villegas,Agnes Wechsler-Fördös,Heiman F. L. Wertheim,Evelyn Wesangula,Neil Woodford,Fidan O Yilmaz,Anna Zorzet +81 more
TL;DR: Future development strategies should focus on antibiotics that are active against multidrug-resistant tuberculosis and Gram-negative bacteria, and include antibiotic-resistant bacteria responsible for community-acquired infections.
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Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks.
TL;DR: Elimination of carriage of S. aureus has been found to reduce the infection rates in surgical patients and those on hemodialysis and CAPD, and those colonized with MRSA.
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Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017
Sandra I. Berríos-Torres,Craig A Umscheid,Dale W. Bratzler,Brian F Leas,Erin C. Stone,Rachel R. Kelz,Caroline E. Reinke,Sherry Morgan,Joseph S. Solomkin,John E. Mazuski,E. Patchen Dellinger,Kamal M.F. Itani,Elie F. Berbari,John Segreti,Javad Parvizi,Joan C. Blanchard,George Allen,Jan Kluytmans,Rodney M. Donlan,William P. Schecter +19 more
TL;DR: This guideline is intended to provide new and updated evidence-based recommendations for the prevention of SSI and should be incorporated into comprehensive surgical quality improvement programs to improve patient safety.
Journal ArticleDOI
Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers.
Heiman F. L. Wertheim,Margreet C. Vos,Alewijn Ott,Alex van Belkum,Andreas Voss,Jan Kluytmans,Peter H. J. van Keulen,Christina M. J. E. Vandenbroucke-Grauls,M. H. M. Meester,Henri A. Verbrugh +9 more
TL;DR: S a Aureus nasal carriers and non-carriers differ significantly in risk and outcome of nosocomial S aureus bacteraemia.
Journal ArticleDOI
Methicillin-resistant Staphylococcus aureus.
Andie S Lee,Andie S Lee,Hermínia de Lencastre,Hermínia de Lencastre,Javier Garau,Jan Kluytmans,Surbhi Malhotra-Kumar,Andreas Peschel,Stéphan Juergen Harbarth +8 more
TL;DR: The success of MRSA is a consequence of the extensive arsenal of virulence factors produced by S. aureus combined with β-lactam resistance and, for most clones, resistance to other antibiotic classes as discussed by the authors.