J
Jeffrey Tsao
Researcher at Novartis
Publications - 31
Citations - 2472
Jeffrey Tsao is an academic researcher from Novartis. The author has contributed to research in topics: Steady-state free precession imaging & Iterative reconstruction. The author has an hindex of 19, co-authored 31 publications receiving 2313 citations. Previous affiliations of Jeffrey Tsao include École Polytechnique Fédérale de Lausanne & University of Zurich.
Papers
More filters
Journal ArticleDOI
k-t BLAST and k-t SENSE: Dynamic MRI with high frame rate exploiting spatiotemporal correlations
TL;DR: Based on this approach, two methods were developed to significantly improve the performance of dynamic imaging, named k‐t BLAST (Broad‐use Linear Acquisition Speed‐up Technique) and k-t SENSE (SENSitivity Encoding) for use with a single or multiple receiver coils, respectively.
Journal ArticleDOI
Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist
Shifeng Pan,Xu Wu,Jiqing Jiang,Wenqi Gao,Yongqin Wan,Dai Cheng,Dong Han,Jun Liu,Nathan P. Englund,Yan Wang,Stefan Peukert,Karen Miller-Moslin,Jing Yuan,Ribo Guo,Melissa Matsumoto,Anthony Vattay,Yun Jiang,Jeffrey Tsao,Fangxian Sun,AnneMarie Culazzo Pferdekamper,Stephanie Kay Dodd,Tove Tuntland,Wieslawa Maniara,Joseph Kelleher,Yung-mae Yao,Markus Warmuth,Juliet Williams,Marion Dorsch +27 more
TL;DR: Structural-activity relationship studies led to the discovery of a potent and specific Smoothened antagonist N-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl- 3-carboxamide (5m, NVP-LDE225), which is currently in clinical development.
Journal ArticleDOI
MRI temporal acceleration techniques.
Jeffrey Tsao,Sebastian Kozerke +1 more
TL;DR: In recent years, there has been an explosive growth of magnetic resonance imaging (MRI) techniques that allow faster scan speed by exploiting temporal or spatiotemporal redundancy of the images as mentioned in this paper.
Journal ArticleDOI
Accelerating cine phase‐contrast flow measurements using k‐t BLAST and k‐t SENSE
Christof Baltes,Sebastian Kozerke,Michael S. Hansen,Klaas P. Pruessmann,Jeffrey Tsao,Peter Boesiger +5 more
TL;DR: K‐t BLAST and k‐t SENSE are promising approaches that permit significant scan‐time reduction in PC velocity mapping, thus making high‐resolution breath‐held flow quantification possible.
Journal ArticleDOI
Accelerating cardiac cine 3D imaging using k-t BLAST.
TL;DR: By shortening the acquisition substantially, k‐t BLAST may greatly facilitate volumetric imaging of the heart for evaluation of regional wall motion and the assessment of ventricular volume and ejection fraction.