J
Joana Sellarés
Researcher at Autonomous University of Barcelona
Publications - 43
Citations - 3534
Joana Sellarés is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Kidney transplantation & Biopsy. The author has an hindex of 17, co-authored 39 publications receiving 2876 citations. Previous affiliations of Joana Sellarés include Hebron University & University of Alberta.
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Journal ArticleDOI
Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence.
Joana Sellarés,D. G. de Freitas,Michael Mengel,Jeff Reeve,Gunilla Einecke,Banu Sis,Luis G. Hidalgo,Konrad S. Famulski,Arthur J. Matas,Philip F. Halloran +9 more
TL;DR: This prospective cohort indicates that many actual failures after indication biopsies manifest phenotypic features of antibody‐mediated or mixed rejection and also underscores the major role of nonadherence.
Journal ArticleDOI
NK cell transcripts and NK cells in kidney biopsies from patients with donor-specific antibodies: evidence for NK cell involvement in antibody-mediated rejection.
L. G. Hidalgo,Banu Sis,Joana Sellarés,Patricia Campbell,Michael Mengel,Gunilla Einecke,J. Chang,Philip F. Halloran +7 more
TL;DR: The strategy of using DSASTs in the biopsy to identify mechanism‐related transcripts in biopsies from patients with clinical phenotypes indicates the selective involvement of NK cells in ABMR.
Journal ArticleDOI
Molecular diagnosis of antibody-mediated rejection in human kidney transplants.
Joana Sellarés,Jeff Reeve,Alexandre Loupy,Michael Mengel,Banu Sis,Alison Skene,D. G. de Freitas,Chatchai Kreepala,Luis G. Hidalgo,Konrad S. Famulski,Philip F. Halloran +10 more
TL;DR: It is concluded that microarray assessment of gene expression can assign a probability of ABMR to transplant biopsies without knowledge of HLA antibody status, histology, or C4d staining, and predicts future failure.
Journal ArticleDOI
Molecular diagnosis of T cell-mediated rejection in human kidney transplant biopsies.
Jeff Reeve,Joana Sellarés,Michael Mengel,Banu Sis,A. Skene,Luis G. Hidalgo,D. G. de Freitas,Konrad S. Famulski,Philip F. Halloran +8 more
TL;DR: A molecular test for T cell‐mediated rejection is developed and new rules to integrate molecular tests and histology into a precision diagnostic system that can reduce errors, ambiguity and interpathologist disagreement are proposed.
Journal ArticleDOI
Disappearance of T Cell-Mediated Rejection Despite Continued Antibody-Mediated Rejection in Late Kidney Transplant Recipients
Philip F. Halloran,Jessica Chang,Konrad S. Famulski,Luis G. Hidalgo,Israel D.R. Salazar,Maribel Merino Lopez,Arthur J. Matas,M. Picton,Declan G. de Freitas,Declan G. de Freitas,Jonathan S. Bromberg,Daniel Serón,Joana Sellarés,Gunilla Einecke,Jeff Reeve +14 more
TL;DR: It is concluded that the main cause of kidney transplant failure is ABMR, which can present even decades after transplantation, implying that a state of partial adaptive tolerance emerges over time in the kidney transplant population.