M
M Goyal
Researcher at Imperial College London
Publications - 3
Citations - 3022
M Goyal is an academic researcher from Imperial College London. The author has contributed to research in topics: Restriction fragment length polymorphism & Mycobacterium tuberculosis. The author has an hindex of 3, co-authored 3 publications receiving 2924 citations.
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Journal ArticleDOI
Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology.
Judith Kamerbeek,Leo M. Schouls,Arend H. J. Kolk,M van Agterveld,D. van Soolingen,Sjoukje Kuijper,Annelies Bunschoten,H Molhuizen,R J Shaw,M Goyal,J. D. A. Van Embden +10 more
TL;DR: A novel method based on strain-dependent hybridization patterns of in vitro-amplified DNA with multiple spacer oligonucleotides was found to differentiate M. bovis from M. tuberculosis, a distinction which is often difficult to make by traditional methods.
Journal ArticleDOI
Differentiation of Mycobacterium tuberculosis isolates by spoligotyping and IS6110 restriction fragment length polymorphism.
TL;DR: Mycobacterium tuberculosis isolates from 167 patients attending three London hospitals were analyzed by two techniques for strain differentiation and use of the two techniques in tandem provided an optimal approach to the identification of clusters with epidemiological evidence consistent with recent transmission.
Journal ArticleDOI
Pulmonary tuberculosis in Harare, Zimbabwe: analysis by spoligotyping
R S Heyderman,M Goyal,Paul T. Roberts,S Ushewokunze,S Zizhou,Ben G. Marshall,Robert Makombe,J. D. A. Van Embden,Peter R. Mason,R J Shaw +9 more
TL;DR: Spoligotyping may yield valuable molecular typing information in populations where tuberculosis culture is not available, but this novel technique requires further development and evaluation in larger epidemiological studies.