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Sjoukje Kuijper

Researcher at University of Amsterdam

Publications -  7
Citations -  2965

Sjoukje Kuijper is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Sputum & Mycobacterium tuberculosis complex. The author has an hindex of 7, co-authored 7 publications receiving 2854 citations. Previous affiliations of Sjoukje Kuijper include Royal Tropical Institute.

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Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology.

TL;DR: A novel method based on strain-dependent hybridization patterns of in vitro-amplified DNA with multiple spacer oligonucleotides was found to differentiate M. bovis from M. tuberculosis, a distinction which is often difficult to make by traditional methods.
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A fast method for the identification of Mycobacterium tuberculosis in sputum and cultures based on thermally assisted hydrolysis and methylation followed by gas chromatography-mass spectrometry

TL;DR: All patients who were diagnosed with TB were also found positive using the newly developed THM-GC-MS method and the results show that the new fast and sensitive THM/GC/MS method holds great potential for the diagnosis of TB.
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Validation of Biomarkers for Distinguishing Mycobacterium tuberculosis from Non-Tuberculous Mycobacteria Using Gas Chromatography−Mass Spectrometry and Chemometrics

TL;DR: A new decision-tree is developed that allows the differentiation of MTB from NTM with 100% accuracy and will proceed with the development of a simple, rapid, affordable, high-throughput test to identify MTB directly in sputum.
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Direct detection of Mycobacterium tuberculosis in sputum using combined solid phase extraction-gas chromatography-mass spectrometry.

TL;DR: A hexane/methanol/water extraction followed by a solid phase extraction (SPE) clean-up procedure was developed for use before THM-GC-MS, to make the test suitable for the identification of mycobacteria in sputum.
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Direct detection of Mycobacterium tuberculosis in sputum: A validation study using solid phase extraction-gas chromatography-mass spectrometry.

TL;DR: A solid phase extraction-gas chromatography-mass spectrometry method for the detection of five biomarkers for M. tuberculosis proved to be reliable and, although complex in principle, easy to operate due to the high degree of automation.