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Maria Dusinska

Researcher at Norwegian Institute for Air Research

Publications -  87
Citations -  7491

Maria Dusinska is an academic researcher from Norwegian Institute for Air Research. The author has contributed to research in topics: Comet assay & Medicine. The author has an hindex of 34, co-authored 51 publications receiving 6761 citations. Previous affiliations of Maria Dusinska include Rowett Research Institute & Slovak Medical University.

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Journal ArticleDOI

The comet assay: what can it really tell us?

TL;DR: The successful measurement of biomarkers of oxidative damage in human populations establishes the comet assay as a valuable tool in molecular epidemiology.
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Comet assay in human biomonitoring studies: Reliability, validation, and applications

TL;DR: The reliability and reproducibility of the comet assay is reported, from the level of comparing results from duplicate gels prepared from the same sample of cells, up to an assessment of the natural intra‐ and interindividual variability in lymphocyte DNA damage measured in groups of normal, healthy human volunteers.
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Oxidative damage to DNA: do we have a reliable biomarker?

TL;DR: Using a revised DNA isolation procedure designed to decrease in vitro oxidation, results are obtained for 8-OHgua concentrations in human lymphocytes that are closure to the figures obtained by the comet assay.
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Mechanisms of genotoxicity. A review of in vitro and in vivo studies with engineered nanoparticles.

TL;DR: The need for appropriate methodologies to be used for investigation of genotoxic effects of NPs, in vitro and in vivo is suggested and advantages and potential problems with different methods are described.