P
Paloma De-La-Quintana
Researcher at Autonomous University of Madrid
Publications - 7
Citations - 1424
Paloma De-La-Quintana is an academic researcher from Autonomous University of Madrid. The author has contributed to research in topics: Stem cell & Randomized controlled trial. The author has an hindex of 6, co-authored 7 publications receiving 1286 citations. Previous affiliations of Paloma De-La-Quintana include Hospital Universitario La Paz.
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Journal ArticleDOI
Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial.
Damián García-Olmo,Dolores Herreros,Isabel Pascual,José Antonio Pascual,Emilio Del-Valle,Jaime Zorrilla,Paloma De-La-Quintana,Mariano García-Arranz,Maria Pascual +8 more
TL;DR: Administration of expanded ASCs (20 to 60 million cells) in combination with fibrin glue is an effective and safe treatment for complex perianal fistula and appears to achieve higher rates of healing than fibr in glue alone.
Journal ArticleDOI
Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: a phase III randomized clinical trial (FATT 1: fistula Advanced Therapy Trial 1) and long-term evaluation.
Maria Dolores Herreros,Mariano García-Arranz,Héctor Guadalajara,Paloma De-La-Quintana,Damián García-Olmo +4 more
TL;DR: In treatment of complex fistula-in-ano, a dose of 20 or 60 million adipose-derived stem cells alone or in combination with fibrin glue was considered a safe treatment, achieving healing rates of approximately 40% at 6 months and of more than 50% at 1-year follow-up.
Journal ArticleDOI
Long-term follow-up of patients undergoing adipose-derived adult stem cell administration to treat complex perianal fistulas
Héctor Guadalajara,Héctor Guadalajara,Dolores Herreros,Paloma De-La-Quintana,Jacobo Trébol,Mariano García-Arranz,Damián García-Olmo +6 more
TL;DR: A low proportion of the stem cell-treated patients with closure after the procedure remained free of recurrence after more than 3 years of follow-up, reaffirmed the very good safety profile of the treatment.
Journal ArticleDOI
Treatment of enterocutaneous fistula in Crohn’s Disease with adipose-derived stem cells: a comparison of protocols with and without cell expansion
Damián García-Olmo,Damián García-Olmo,Dolores Herreros,Maria Pascual,Isabel Pascual,Paloma De-La-Quintana,Jacobo Trébol,Mariano García-Arranz,Mariano García-Arranz +8 more
TL;DR: Although a comparison of case series cannot be considered firm evidence, a therapeutic protocol that uses expansion prior to implantation does seem to be more effective than one that uses SVF cells directly from a lipoaspirate sample.
Journal ArticleDOI
Adipose-Derived Stem Cells in Crohn's Rectovaginal Fistula
Dolores C. García-Olmo,Dolores Herreros,Paloma De-La-Quintana,Héctor Guadalajara,Jacobo Trébol,T. Georgiev-Hristov,Mariano García-Arranz +6 more
TL;DR: The conclusion of the study with Mary is that the use of mesenchymal stem cells derived from adipose tissue is secure, either in autologous or allogeneic form, which confirms the safety of using these cells in patients at least in the fistulizing Crohn's disease environment.