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Bart Staels

Researcher at Pasteur Institute

Publications -  868
Citations -  96167

Bart Staels is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Peroxisome proliferator-activated receptor & Nuclear receptor. The author has an hindex of 152, co-authored 824 publications receiving 86638 citations. Previous affiliations of Bart Staels include University of California, San Francisco & The Catholic University of America.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism

Bart Staels, +5 more
- 10 Nov 1998 - 
TL;DR: Both enhanced catabolism of triglyceride-rich particles and reduced secretion of VLDL underlie the hypotriglyceridemic effect of fibrates, whereas their effect on HDL metabolism is associated with changes in HDL apolipoprotein expression.
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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

Philippe Lefebvre, +4 more
- 01 Jan 2009 - 
TL;DR: Results suggest that modulation of FXR activity and BA metabolism may open new attractive pharmacological approaches for the treatment of the metabolic syndrome and type 2 diabetes.
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The organization, promoter analysis, and expression of the human PPARgamma gene.

Lluis Fajas, +15 more
- 25 Jul 1997 - 
TL;DR: This work determined that high level expression of PPARγ in colon warrants further study in view of the well established role of fatty acid and arachidonic acid derivatives in colonic disease and its promoters and tissue-specific expression were functionally characterized.
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Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression.

Kristina Schoonjans, +2 more
- 01 May 1996 - 
TL;DR: It is suggested that PPARs are key messengers responsible for the translation of nutritional and pharmacological stimuli into changes in gene expression and differentiation pathways.