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Vijay Kumar

Researcher at Defence Institute of Advanced Technology

Publications -  27
Citations -  4919

Vijay Kumar is an academic researcher from Defence Institute of Advanced Technology. The author has contributed to research in topics: Vascular endothelial growth factor C & Vascular endothelial growth factor. The author has an hindex of 15, co-authored 22 publications receiving 4699 citations. Previous affiliations of Vijay Kumar include University of Helsinki & Ohio State University.

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Proteolytic processing regulates receptor specificity and activity of VEGF-C

TL;DR: The role of post‐translational processing in VEGF‐C secretion and function is analysed, and novel structure–function relationships in the PDGF/VEGF family are revealed.
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Vascular endothelial growth factor C induces angiogenesis in vivo

TL;DR: VEGF-C may regulate physiological angiogenesis and participate in the development and progression of angiogenic diseases in addition to lymphangiogenesis, and is sufficiently potent to stimulate neovascularization from limbal vessels in the mouse cornea.
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Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells.

TL;DR: The binding of VEGF-B to its receptor on endothelial cells leads to increased expression and activity of urokinase type plasminogen activator and plasmineg activator inhibitor 1, suggesting a role for VEGf-B in the regulation of extracellular matrix degradation, cell adhesion, and migration.
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Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

TL;DR: The results reveal that the three VEGF genes are regulated in a strikingly different manner, suggesting that they serve distinct, although perhaps overlapping functions in vivo.