Journal ArticleDOI
Antioxidant activity and phenolic compounds of ginger (Zingiber officinale Rosc.) determined by HPLC-MS/MS
Hatice Tohma,İlhami Gülçin,İlhami Gülçin,Ercan Bursal,Ahmet C. Gören,Saleh Alwasel,Ekrem Köksal +6 more
TLDR
In this article, the authors evaluated the antioxidant properties of ginger (Zingiber officinale Rosc.) based on three parameters: the antioxidant capacity, total phenolic and flavonoid content as well as identification of phenolic acids of water extract (WEG) and ethanol extract (EEG) of ginger.Abstract:
Oxidative stress related diseases often arise from over production of free radicals and reactive oxygen/nitrogen species. The prevention of these diseases could be possible with the use of natural antioxidant plants that could be promising as therapeutic candidates. Since antioxidant properties of a species could be stem from phenolic compounds, it is, therefore, important to evaluate antioxidant and total/individual phenolic and flavonoid content. For this purpose, we evaluated antioxidant properties of ginger (Zingiber officinale Rosc.) based on three parameters: the antioxidant capacity, total phenolic and flavonoid content as well as identification of phenolic acids of water extract (WEG) and ethanol extract (EEG) of ginger. For antioxidant capacity, we performed FRAP, CUPRAC assay, Fe2+ chelating ability, DPPH and DMPD radical scavenging activities. Also, total phenolic and flavonoid contents in both extracts were also measured via Folin Ciocalteu’s method. For identification of phenolic acids, HPLC-MS/MS method was performed. The results showed that EEG had generally better antioxidant activity than WEG in all assays. HPLC-MS/MS analysis showed that there are at least eight different phenolic acids found in ginger, among which pyrogallol p-hydroxybenzoic acid, ferulic acid and p-coumaric acid were more abundant in both extracts. This study clearly showed that ginger extracts demonstrated effective antioxidant properties and their consumption may reduce or delay the progression of diseases that oxidative stress take place due to lack of antioxidant supplementation.read more
Citations
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Antioxidants and antioxidant methods: an updated overview
TL;DR: Antioxidants had a growing interest owing to their protective roles in food and pharmaceutical products against oxidative deterioration and in the body and against oxidative stress-mediated pathological processes as discussed by the authors, and many studies evaluating the antioxidant activity of various samples of research interest have been conducted.
Journal ArticleDOI
Antioxidant and anticholinergic properties of olivetol
Parham Taslimi,İlhami Gülçin +1 more
Journal ArticleDOI
Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions.
TL;DR: The novel bromophenols demonstrate powerful antioxidant activities when compared to standard antioxidant molecules of α-tocopherol, trolox, butylated hydroxyanisole (BHA), andbutylated hydroxytoluene (BHT).
Journal ArticleDOI
Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials
Shokoh Parham,Anousheh Zargar Kharazi,Hamid Reza Bakhsheshi-Rad,Hamid Reza Bakhsheshi-Rad,Hadi Nur,Ahmad Fauzi Ismail,Safian Sharif,Seeram Ramakrishna,Filippo Berto +8 more
TL;DR: In this paper, the authors highlight the antibacterial, antiviral, and radical scavenger (antioxidant) properties of herbal materials, including clove, portulaca, tribulus, eryngium, cinnamon, turmeric, ginger, thyme, pennyroyal, mint, fennel, chamomile, burdock, eucalyptus, primrose, lemon balm, mallow, and garlic.
Journal ArticleDOI
Beneficial effects of ginger on prevention of obesity through modulation of gut microbiota in mice
TL;DR: Modulation of the gut microbiota as a result of ginger supplementation has a therapeutic effect on obesity in mice, and anti-obesity and microbiota-modulating effects similar to those observed in the oral ginger-feeding experiment are suggested.
References
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Journal ArticleDOI
Chemical constituents and their bioactivities of "Tongling White Ginger" (Zingiber officinale).
TL;DR: Two novel gingerdione dimers are isolated and identified and two new gingerol derivatives, (5R)-5-acetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan- 3-one and methyl (Z)-neral acetal-[6]-gingerdiol (4) are identified from rhizomes of Zingiber officinale collected from Tongling, China.
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Evaluation of the efficacy of ginger, Arabic gum, and Boswellia in acute and chronic renal failure.
TL;DR: Ginger and AG could be beneficial adjuvant therapy in patients with acute renal failure and CRF to prevent disease progression and delay the need for renal replacement therapy.
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Ginger extract modulates Pb-induced hepatic oxidative stress and expression of antioxidant gene transcripts in rat liver
TL;DR: GE has an antioxidant protective efficacy against PbAc-induced hepatotoxicity, which appears more effective than its therapeutic application, however, the changes in antioxidant gene expression were not reflected at the protein level.
Journal ArticleDOI
Antioxidant and androgenic effects of dietary ginger on reproductive function of male diabetic rats
Zohra Ghlissi,Rim Atheymen,Mouhamed Ali Boujbiha,Zouheir Sahnoun,Fatma Ayedi,Khaled Mounir Zeghal,Abdelfattah El Feki,Ahmed Hakim +7 more
TL;DR: In this article, the antioxidant and androgenic properties of ginger roots on the reproductive function of male diabetic rats were evaluated, and the results showed that intake of ginger root improves the male reproductive function.