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Alfred H. Merrill
Researcher at Georgia Institute of Technology
Publications - 289
Citations - 33441
Alfred H. Merrill is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: Sphingolipid & Sphingosine. The author has an hindex of 91, co-authored 288 publications receiving 30943 citations. Previous affiliations of Alfred H. Merrill include Emory University & Tufts Medical Center.
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Journal ArticleDOI
A comprehensive classification system for lipids
Eoin Fahy,Shankar Subramaniam,H. Alex Brown,Christopher K. Glass,Alfred H. Merrill,Robert C. Murphy,Christian R. H. Raetz,David W. Russell,Yousuke Seyama,Walter A. Shaw,Takao Shimizu,Friedrich Spener,Gerrit van Meer,Michael S. VanNieuwenhze,Stephen H. White,Joseph L. Witztum,Edward A. Dennis +16 more
TL;DR: A comprehensive classification of lipids with a common platform that is compatible with informatics requirements has been developed to deal with the massive amounts of data that will be generated by the lipid community.
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Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets
TL;DR: It is suggested that sphingosine will be a useful inhibitor for investigating the function of protein kinase C in vitro and in living cells.
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Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme.
TL;DR: Findings suggest that disruption of the de novo pathway of sphingolipid biosynthesis may be a critical event in the diseases that have been associated with consumption of fumonisins.
Journal ArticleDOI
Lipidomics reveals a remarkable diversity of lipids in human plasma
Oswald Quehenberger,Aaron M. Armando,Alex Brown,Stephen B. Milne,David S. Myers,Alfred H. Merrill,Sibali Bandyopadhyay,Kristin N. Jones,Samuel Kelly,Rebecca L. Shaner,Cameron Sullards,Elaine Wang,Robert C. Murphy,Robert M. Barkley,Thomas J. Leiker,Christian R. H. Raetz,Ziqiang Guan,Gregory M. Laird,David A. Six,David W. Russell,Jeffrey G. McDonald,Shankar Subramaniam,Eoin Fahy,Edward A. Dennis +23 more
TL;DR: The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids and to quantitatively assessed the levels of over 500 distinct molecular species distributed among the main lipid categories.
Journal ArticleDOI
LMSD: LIPID MAPS structure database.
Manish Sud,Eoin Fahy,Dawn Cotter,Alex Brown,Edward A. Dennis,Christopher K. Glass,Alfred H. Merrill,Robert C. Murphy,Christian R. H. Raetz,David W. Russell,Shankar Subramaniam +10 more
TL;DR: The LIPID MAPS Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids that provides the capability to perform a substructure search or exact match for the structure drawn by the user.