G
Gerrit van Meer
Researcher at Utrecht University
Publications - 75
Citations - 16424
Gerrit van Meer is an academic researcher from Utrecht University. The author has contributed to research in topics: Membrane lipids & Lipid raft. The author has an hindex of 38, co-authored 75 publications receiving 14632 citations. Previous affiliations of Gerrit van Meer include University of Amsterdam & Hungarian Academy of Sciences.
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Journal ArticleDOI
Membrane lipids: where they are and how they behave.
TL;DR: How do cells apply anabolic and catabolic enzymes, translocases and transporters, plus the intrinsic physical phase behaviour of lipids and their interactions with membrane proteins, to create the unique compositions and multiple functions of their individual membranes?
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A comprehensive classification system for lipids
Eoin Fahy,Shankar Subramaniam,H. Alex Brown,Christopher K. Glass,Alfred H. Merrill,Robert C. Murphy,Christian R. H. Raetz,David W. Russell,Yousuke Seyama,Walter A. Shaw,Takao Shimizu,Friedrich Spener,Gerrit van Meer,Michael S. VanNieuwenhze,Stephen H. White,Joseph L. Witztum,Edward A. Dennis +16 more
TL;DR: A comprehensive classification of lipids with a common platform that is compatible with informatics requirements has been developed to deal with the massive amounts of data that will be generated by the lipid community.
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Update of the LIPID MAPS comprehensive classification system for lipids
Eoin Fahy,Shankar Subramaniam,Robert C. Murphy,Masahiro Nishijima,Christian R. H. Raetz,Takao Shimizu,Friedrich Spener,Gerrit van Meer,Michael J.O. Wakelam,Edward A. Dennis +9 more
TL;DR: The International Lipid Classification and Nomenclature Committee under the sponsorship of the LIPID MAPS Consortium developed and established a "Comprehensive Classification System for Lipids" based on well defined chemical and biochemical principles and using an ontology that is extensible, flexible, and scalable as mentioned in this paper.
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MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine
Ardy van Helvoort,Alexander J. Smith,Hein Sprong,Ingo Fritzsche,Alfred H. Schinkel,Piet Borst,Gerrit van Meer +6 more
TL;DR: After stable transfection of epithelial LLC-PK1 cells, MDR1 and MDR3 Pgp were localized in the apical membrane and newly synthesized short-chain analogs of various membrane lipids were recovered in theApical albumin-containing medium of MDR 1 cells but not control cells.
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The cell biology of lysosomal storage disorders.
TL;DR: The biochemistry of lysosomal storage disorders is summarized and downstream cellular pathways that are potentially affected in these disorders are discussed and that might help to delineate their pathological mechanisms.