C
Conny Höflich
Researcher at Charité
Publications - 30
Citations - 2472
Conny Höflich is an academic researcher from Charité. The author has contributed to research in topics: Cytokine & Cytotoxic T cell. The author has an hindex of 18, co-authored 29 publications receiving 2263 citations. Previous affiliations of Conny Höflich include Humboldt University of Berlin & Humboldt State University.
Papers
More filters
Journal ArticleDOI
Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation.
Konstantin Prass,Christian Meisel,Conny Höflich,Johann S. Braun,E. Halle,Tilo Wolf,Karsten Ruscher,Ilya V. Victorov,Josef Priller,Ulrich Dirnagl,Hans-Dieter Volk,Andreas Meisel +11 more
TL;DR: It is suggested that a catecholamine-mediated defect in early lymphocyte activation is the key factor in the impaired antibacterial immune response after stroke.
Journal ArticleDOI
Immunopathogenesis of psoriasis
Robert Sabat,Sandra Philipp,Conny Höflich,Stefanie Kreutzer,Elizabeth Wallace,Khusru Asadullah,Hans-Dieter Volk,Wolfram Sterry,Kerstin Wolk +8 more
TL;DR: It is postulated that the pathogenesis of psoriasis consists of distinct subsequent stages, in each of them different cell types playing a dominant role, which helps to explain the varied effectiveness of the currently tested immune modulating therapies and may enable the prediction of the success of future therapies.
Journal ArticleDOI
Monitoring temporary immunodepression by flow cytometric measurement of monocytic HLA-DR expression: a multicenter standardized study.
Wolf-Dietrich Döcke,Conny Höflich,Kenneth A. Davis,Karsten Röttgers,Christian Meisel,Paul Kiefer,Stefan Weber,Monika Hedwig-Geissing,Ernst Kreuzfelder,Peter Tschentscher,Thomas Nebe,Andrea Engel,Guillaume Monneret,Andreas Spittler,Kathrin Schmolke,Petra Reinke,Hans-Dieter Volk,Dagmar Kunz +17 more
TL;DR: For the BD Quantibrite HLA-DR/Monocyte test, preanalytical handling is standardized and results demonstrated the independence of this test from flow cytometer and instrument settings.
Journal ArticleDOI
Naturally occurring anti–IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans
Conny Höflich,Robert Sabat,Simone Rosseau,Bettina Temmesfeld,Hortense Slevogt,Wolf-Dietrich Döcke,Gerald Grütz,Christian Meisel,Elke Halle,Ulf B. Göbel,Hans-Dieter Volk,Norbert Suttorp +11 more
TL;DR: Screening for neutralizing anti-IFN-Gamma autoantibodies should supplement testing for IFN-gamma and IL-12 pathway defects in patients with recurrent infections with intracellular pathogens, especially with nontuberculous mycobacteria.
Journal ArticleDOI
Preoperative high‐dose steroid administration attenuates the surgical stress response following liver resection: results of a prospective randomized study
Sven Schmidt,Susanne Hamann,Jan M. Langrehr,Conny Höflich,Jens Mittler,Dictmar Jacob,Peter Neuhaus +6 more
TL;DR: Intravenous methylprednisolone administration before hepatic resection significantly reduced systemic inflammatory cytokine release and the convalescence score and the length of hospital stay in the steroid group.