E
Elizabeth Wallace
Researcher at Charité
Publications - 4
Citations - 1584
Elizabeth Wallace is an academic researcher from Charité. The author has contributed to research in topics: Interleukin 20 & Psoriasis. The author has an hindex of 4, co-authored 4 publications receiving 1486 citations.
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Journal ArticleDOI
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes : a potential role in psoriasis
Kerstin Wolk,Ellen Witte,Elizabeth Wallace,Wolf-Dietrich Döcke,Stefanie Kunz,Khusru Asadullah,Hans-Dieter Volk,Wolfram Sterry,Robert Sabat +8 more
TL;DR: It is demonstrated that IL‐22, in contrast to its relative IFN‐γ, regulates the expression of only a few genes in keratinocytes, which may be important in the innate immunity and reorganization of epithelia.
Journal ArticleDOI
Immunopathogenesis of psoriasis
Robert Sabat,Sandra Philipp,Conny Höflich,Stefanie Kreutzer,Elizabeth Wallace,Khusru Asadullah,Hans-Dieter Volk,Wolfram Sterry,Kerstin Wolk +8 more
TL;DR: It is postulated that the pathogenesis of psoriasis consists of distinct subsequent stages, in each of them different cell types playing a dominant role, which helps to explain the varied effectiveness of the currently tested immune modulating therapies and may enable the prediction of the success of future therapies.
Journal ArticleDOI
IL-19 and IL-20: two novel cytokines with importance in inflammatory diseases
TL;DR: Results from animal experiments and massively increased expression of these mediators in human inflamed tissues support the assumption that they play an important role in the pathogenesis of a few inflammatory diseases.
Journal ArticleDOI
The evaluation of psoriasis therapy with biologics leads to a revision of the current view of the pathogenesis of this disorder
Sandra Philipp,Kerstin Wolk,Stephanie Kreutzer,Elizabeth Wallace,Nina Ludwig,Joachim Roewert,Conny Höflich,Hans-Dieter Volk,Wolfram Sterry,Robert Sabat +9 more
TL;DR: The authors critically re-evaluated the view of psoriasis pathogenesis and postulate that in the majority of patients the T1 cells do not play a dominant role in the clinical, visible stage of this disease.