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Françoise Clavel-Chapelon
Researcher at Institut Gustave Roussy
Publications - 534
Citations - 55265
Françoise Clavel-Chapelon is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: European Prospective Investigation into Cancer and Nutrition & Prospective cohort study. The author has an hindex of 118, co-authored 534 publications receiving 50006 citations. Previous affiliations of Françoise Clavel-Chapelon include National Institutes of Health & Université Paris-Saclay.
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Journal ArticleDOI
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Lionel Apetoh,François Ghiringhelli,Antoine Tesniere,Antoine Tesniere,Antoine Tesniere,Michel Obeid,Michel Obeid,Michel Obeid,Carla Ortiz,Carla Ortiz,Carla Ortiz,Alfredo Criollo,Alfredo Criollo,Alfredo Criollo,Grégoire Mignot,Grégoire Mignot,Grégoire Mignot,M. Chiara Maiuri,Evelyn Ullrich,Evelyn Ullrich,Evelyn Ullrich,Patrick Saulnier,Huan Yang,Sebastian Amigorena,Bernard Ryffel,Franck J. Barrat,Paul Saftig,Francis Lévi,Francis Lévi,Rosette Lidereau,Catherine Noguès,Jean-Paul Mira,Agnès Chompret,Virginie Joulin,Françoise Clavel-Chapelon,Jean Bourhis,Fabrice Andre,Suzette Delaloge,T. Tursz,Guido Kroemer,Guido Kroemer,Guido Kroemer,Laurence Zitvogel +42 more
TL;DR: A previously unrecognized pathway for the activation of tumor antigen–specific T-cell immunity that involves secretion of the high-mobility-group box 1 (HMGB1) alarmin protein by dying tumor cells and the action of HMGB1 on Toll-like receptor 4 (TLR4) expressed by dendritic cells (DCs) is described.
Journal ArticleDOI
General and abdominal adiposity and risk of death in Europe.
Tobias Pischon,Heiner Boeing,Kurt Hoffmann,M. Bergmann,Matthias B. Schulze,Kim Overvad,Y. T. van der Schouw,Elizabeth A Spencer,Karel G.M. Moons,Anne Tjønneland,Jytte Halkjær,Majken K. Jensen,Jakob Stegger,Françoise Clavel-Chapelon,M. C. Boutron-Ruault,V. Chajes,Jakob Linseisen,Rudolf Kaaks,Antonia Trichopoulou,Dimitrios Trichopoulos,Christina Bamia,Sabina Sieri,Domenico Palli,Rosario Tumino,Paolo Vineis,Paolo Vineis,Salvatore Panico,Petra H.M. Peeters,A. M. May,H. B. Bueno-de-Mesquita,F. J. B. van Duijnhoven,Göran Hallmans,Lars Weinehall,Jonas Manjer,Bo Hedblad,Eiliv Lund,Antonio Agudo,L. Arriola,Aurelio Barricarte,Carmen Navarro,Carlos Martinez,J. R. Quirós,Timothy J. Key,Sheila Bingham,Kay-Tee Khaw,Paolo Boffetta,Mazda Jenab,Pietro Ferrari,Elio Riboli +48 more
TL;DR: It is suggested that both general adiposity and abdominal adiposity are associated with the risk of death and support the use of waist circumference or waist-to-hip ratio in addition to BMI in assessing therisk of death.
Journal ArticleDOI
European prospective investigation into cancer and nutrition (EPIC): study populations and data collection
Elio Riboli,Kelly J. Hunt,Nadia Slimani,Pietro Ferrari,Teresa Norat,Michael T. Fahey,Charrondière Ur,Bertrand Hémon,Corinne Casagrande,Jérôme Vignat,Kim Overvad,Anne Tjønneland,Françoise Clavel-Chapelon,Anne C. M. Thiébaut,Jürgen Wahrendorf,Heiner Boeing,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Antonia Trichopoulou,Paolo Vineis,Domenico Palli,H. B. Bueno-De-Mesquita,Petra H.M. Peeters,Eiliv Lund,Dagrun Engeset,Carlos A. González,Aurelio Barricarte,Göran Berglund,Göran Hallmans,Nicholas E. Day,Timothy J. Key,Rudolf Kaaks,R. Saracci +32 more
TL;DR: The present paper provides a description of theEPIC study, with the aim of simplifying reference to it in future papers reporting substantive or methodological studies carried out in the EPIC cohort.
Journal ArticleDOI
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
Rayjean J. Hung,James McKay,Valerie Gaborieau,Paolo Boffetta,Mia Hashibe,David Zaridze,Anush Mukeria,Neonilia Szeszenia-Dabrowska,Jolanta Lissowska,Peter Rudnai,Eleonora Fabianova,Dana Mates,Vladimir Bencko,Lenka Foretova,Vladimir Janout,Chu Chen,Gary E. Goodman,John K. Field,Triantafillos Liloglou,George Xinarianos,Adrian Cassidy,John R. McLaughlin,Geoffrey Liu,Steven A. Narod,Hans E. Krokan,Frank Skorpen,Maiken Bratt Elvestad,Kristian Hveem,Lars J. Vatten,Jakob Linseisen,Françoise Clavel-Chapelon,Paolo Vineis,H. Bas Bueno-de-Mesquita,Eiliv Lund,Carmen Martinez,Sheila Bingham,Torgny Rasmuson,Pierre Hainaut,Elio Riboli,Wolfgang Ahrens,Simone Benhamou,Pagona Lagiou,Dimitrios Trichopoulos,Ivana Holcatova,Franco Merletti,Kristina Kjærheim,Antonio Agudo,Gary J. Macfarlane,Renato Talamini,Lorenzo Simonato,Ray Lowry,David I. Conway,Ariana Znaor,Claire M. Healy,Diana Zelenika,Anne Boland,Marc Delepine,Mario Foglio,Doris Lechner,Fumihiko Matsuda,Hélène Blanché,Ivo Gut,Simon Heath,Mark Lathrop,Paul Brennan +64 more
TL;DR: The results provide compelling evidence of a locus at 15q25 predisposing to lung cancer, and reinforce interest in nicotinic acetylcholine receptors as potential disease candidates and chemopreventative targets.
Journal ArticleDOI
Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study
Sheila Bingham,Nicholas E. Day,Robert Luben,Pietro Ferrari,Nadia Slimani,Teresa Norat,Françoise Clavel-Chapelon,Emmanuelle Kesse,Alexandra Nieters,Heiner Boeing,Anne Tjϕnneland,Kim Overvad,Carmen Martinez,Miren Dorronsoro,Carlos A. González,Timothy J. Key,Antonia Trichopoulou,Androniki Naska,Paolo Vineis,Rosario Tumino,Vittorio Krogh,H. Bas Bueno-de-Mesquita,Petra H.M. Peeters,Göran Berglund,Göran Hallmans,Eiliv Lund,Guri Skeie,Rudolf Kaaks,Elio Riboli +28 more
TL;DR: Dietary fibre in foods was inversely related to incidence of large bowel cancer, with the protective effect being greatest for the left side of the colon, and least for the rectum.