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Robert Svirskas
Researcher at Howard Hughes Medical Institute
Publications - 15
Citations - 9654
Robert Svirskas is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Connectome & Genome. The author has an hindex of 10, co-authored 13 publications receiving 8653 citations. Previous affiliations of Robert Svirskas include GE Healthcare & Motorola.
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Journal ArticleDOI
The genome sequence of Drosophila melanogaster
Mark Raymond Adams,Susan E. Celniker,Robert A. Holt,Cheryl A. Evans,Jeannine D. Gocayne,Peter Amanatides,Steve Scherer,Peter W. Li,Roger A. Hoskins,R. Galle,Reed A. George,Suzanna E. Lewis,Stephen Richards,Michael Ashburner,Scott Henderson,Granger G. Sutton,Jennifer R. Wortman,Mark Yandell,Qing Zhang,Lin Chen,Rhonda C. Brandon,Yu-Hui Rogers,R. Blazej,Mark Champe,Barret D. Pfeiffer,Kenneth H. Wan,Colleen Doyle,E. G. Baxter,Gregg Helt,Catherine R. Nelson,G. L. Gabor Miklos,Josep F. Abril,A. Agbayani,Huijin An,C. Andrews-Pfannkoch,Danita Baldwin,Richard M. Ballew,Anand Basu,James Baxendale,Leyla Bayraktaroglu,Ellen M. Beasley,Karen Beeson,Panayiotis V. Benos,Benjamin P. Berman,D. Bhandari,Slava Bolshakov,Dana Borkova,Michael R. Botchan,John Bouck,Peter Brokstein,Philippe Brottier,Kenneth C. Burtis,Dana A. Busam,Heather Butler,Edouard Cadieu,I. Chandra,J. Michael Cherry,Simon Cawley,Carl Dahlke,Lionel Davenport,P. Davies,B. de Pablos,Arthur L. Delcher,Zuoming Deng,A. Deslattes Mays,Ian M. Dew,Susanne Dietz,Kristina Dodson,Lisa Doup,Michael Downes,Shannon Dugan-Rocha,B. C. Dunkov,Patrick J. Dunn,K. J. Durbin,Carlos Evangelista,Concepcion Ferraz,Steven Ferriera,Wolfgang Fleischmann,Carl Fosler,Andrei Gabrielian,Neha Garg,William M. Gelbart,Kenneth Glasser,A. Glodek,Fangcheng Gong,J. Harley Gorrell,Zhiping Gu,Ping Guan,Michael Harris,Nomi L. Harris,Damon A. Harvey,Thomas J. Heiman,Judith Hernandez,Jarrett Houck,Damon Hostin,K. Houston,Timothy Howland,Ming-Hui Wei,Chinyere Ibegwam,M. Jalali,Francis Kalush,Gary H. Karpen,Zhaoxi Ke,James A. Kennison,K. A. Ketchum,B. E. Kimmel,Chinnappa D. Kodira,Cheryl L. Kraft,Saul A. Kravitz,David Kulp,Zhongwu Lai,Paul Lasko,Yiding Lei,Alexander Levitsky,Jun Li,Zhenya Li,Yunye Liang,Xiaoying Lin,Xiangjun Liu,B. Mattei,Tina C. McIntosh,Michael P. McLeod,D. McPherson,Gennady V. Merkulov,Natalia Milshina,Clark M. Mobarry,J. Morris,A. Moshrefi,Stephen M. Mount,Mee Moy,Brian Murphy,Lee Murphy,Donna M. Muzny,David L. Nelson,David R. Nelson,Keith Nelson,K. Nixon,Deborah R. Nusskern,Joanne Pacleb,Michael J. Palazzolo,G. S. Pittman,Sue Pan,J. Pollard,Vinita Puri,Martin G. Reese,Knut Reinert,Karin A. Remington,Robert D. C. Saunders,Robert D. C. Saunders,F. Scheeler,H. Shen,B. Christopher Shue,Inga Siden-Kiamos,Michael Simpson,Marian P. Skupski,Thomas J. Smith,Eugene G. Spier,Allan C. Spradling,Mark Stapleton,Renee Strong,E. Sun,Robert Svirskas,C. Tector,Russell Turner,Eli Venter,Aihui Wang,Xianyuan Wang,Zhen Yuan Wang,David A. Wassarman,George M. Weinstock,Jean Weissenbach,Sherita Williams,Trevor Woodage,Kim C. Worley,D. Wu,Shih-Hung Yang,Q. Alison Yao,Jane Ye,R. F. Yeh,Jayshree Zaveri,Ming Zhan,Gefei Zhang,Qi Zhao,Liansheng Zheng,Xiangqun Zheng,Fei Zhong,Wenyan Zhong,X. Zhou,Shiaoping C. Zhu,Xiancan Zhu,Hamilton O. Smith,Richard A. Gibbs,Eugene W. Myers,Gerald M. Rubin,J. Craig Venter +194 more
TL;DR: The nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome is determined using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map.
Journal ArticleDOI
A GAL4-Driver Line Resource for Drosophila Neurobiology
Arnim Jenett,Gerald M. Rubin,Teri-T B. Ngo,David Shepherd,Christine Murphy,Heather Dionne,Barret D. Pfeiffer,Amanda Cavallaro,Donald Hall,Jennifer Jeter,Nirmala Iyer,Dona Fetter,Joanna H. Hausenfluck,Hanchuan Peng,Eric T. Trautman,Robert Svirskas,Eugene W. Myers,Zbigniew R. Iwinski,Yoshinori Aso,Gina M. DePasquale,Adrianne Enos,Phuson Hulamm,S. Lam,Hsing-Hsi Li,Todd R. Laverty,Fuhui Long,Lei Qu,Sean D. Murphy,Konrad Rokicki,Todd Safford,Kshiti Shaw,Julie H. Simpson,Allison Sowell,Susana Tae,Yang Yu,Christopher T. Zugates +35 more
TL;DR: The utility of 7,000 transgenic lines of Drosophila melanogaster for identifying novel neuronal cell types, revealing brain asymmetry, and describing the nature and extent of neuronal shape stereotypy is illustrated.
Journal ArticleDOI
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective
Joshua S. Kaminker,Casey M. Bergman,Brent Kronmiller,Brent Kronmiller,Joseph W. Carlson,Robert Svirskas,Sandeep Patel,Erwin Frise,David A. Wheeler,Suzanna E. Lewis,Gerald M. Rubin,Gerald M. Rubin,Gerald M. Rubin,Michael Ashburner,Susan E. Celniker +14 more
TL;DR: This analysis represents an initial characterization of the transposable elements in the Release 3 euchromatic genomic sequence of D. melanogaster for which comparison to the transPOSable elements of other organisms can begin to be made.
Journal ArticleDOI
A connectome and analysis of the adult Drosophila central brain
Louis K. Scheffer,C. Shan Xu,Michał Januszewski,Zhiyuan Lu,Zhiyuan Lu,Shin-ya Takemura,Kenneth J. Hayworth,Gary B. Huang,Kazunori Shinomiya,Jeremy Maitlin-Shepard,Stuart Berg,Jody Clements,Philip M Hubbard,William T. Katz,Lowell Umayam,Ting Zhao,David G. Ackerman,Tim Blakely,John A. Bogovic,Tom Dolafi,Dagmar Kainmueller,Takashi Kawase,Khaled Khairy,Laramie Leavitt,Peter H. Li,Larry Lindsey,Nicole Neubarth,Donald J. Olbris,Hideo Otsuna,Eric T. Trautman,Masayoshi Ito,Masayoshi Ito,Alexander Shakeel Bates,Jens Goldammer,Jens Goldammer,Tanya Wolff,Robert Svirskas,Philipp Schlegel,Erika Neace,Christopher J Knecht,Chelsea X Alvarado,Dennis A Bailey,Samantha Ballinger,Jolanta A. Borycz,Brandon S Canino,Natasha Cheatham,Michael A Cook,Marisa Dreher,Octave Duclos,Bryon Eubanks,Kelli Fairbanks,Samantha Finley,Nora Forknall,Audrey Francis,Gary Patrick Hopkins,Emily M Joyce,SungJin Kim,Nicole A Kirk,Julie Kovalyak,Shirley Lauchie,Alanna Lohff,Charli Maldonado,Emily A Manley,Sari McLin,Caroline Mooney,Miatta Ndama,Omotara Ogundeyi,Nneoma Okeoma,Christopher Ordish,Nicholas Padilla,Christopher Patrick,Tyler Paterson,Elliott E Phillips,Emily M Phillips,Neha Rampally,Caitlin Ribeiro,Madelaine K Robertson,Jon Thomson Rymer,Sean M Ryan,Megan Sammons,Anne K Scott,Ashley L Scott,Aya Shinomiya,Claire Smith,Kelsey Smith,Natalie L Smith,Margaret A Sobeski,Alia Suleiman,Jackie Swift,Satoko Takemura,Iris Talebi,Dorota Tarnogorska,Emily Tenshaw,Temour Tokhi,John J. Walsh,Tansy Yang,Jane Anne Horne,Feng Li,Ruchi Parekh,Patricia K. Rivlin,Vivek Jayaraman,Marta Costa,Gregory S.X.E. Jefferis,Gregory S.X.E. Jefferis,Kei Ito,Kei Ito,Kei Ito,Stephan Saalfeld,Reed A. George,Ian A. Meinertzhagen,Ian A. Meinertzhagen,Gerald M. Rubin,Harald F. Hess,Viren Jain,Stephen M. Plaza +114 more
TL;DR: Improved methods are summarized and the circuitry of a large fraction of the brain of the fruit fly Drosophila melanogaster is presented, reducing the effort needed to answer circuit questions and providing procedures linking the neurons defined by the analysis with genetic reagents.
Journal ArticleDOI
Finishing a whole-genome shotgun: Release 3 of the Drosophila melanogaster euchromatic genome sequence
Susan E. Celniker,David A. Wheeler,Brent Kronmiller,Joseph W. Carlson,Aaron L. Halpern,Sandeep Patel,Mark Raymond Adams,Mark Champe,Shannon Dugan,Erwin Frise,Ann Hodgson,Reed A. George,Roger A. Hoskins,Todd R. Laverty,Donna M. Muzny,Catherine R Nelson,Joanne Pacleb,Soo Park,Barret D. Pfeiffer,Stephen Richards,Stephen Richards,Erica Sodergren,Robert Svirskas,Paul E. Tabor,Kenneth H. Wan,Mark Stapleton,Granger G. Sutton,Craig Venter,George M. Weinstock,Steven E. Scherer,Eugene W. Myers,Richard A. Gibbs,Gerald M. Rubin,Gerald M. Rubin +33 more
TL;DR: The WGS strategy can efficiently produce a high-quality sequence of a metazoan genome while generating the reagents required for sequence finishing, however, the initial method of repeat assembly was flawed.